SCHEMBL1993032

SCHEMBL1993032

CCCCOC(CC(=O)O)(CC(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
HSPD1 P10809 1/20 0.38
BLM P54132 1/20 0.38
HSPE1 P61604 1/20 0.38
LMNA P02545 1/20 0.37
TSHR P16473 5/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
AKR1B1 P15121 1/20 0.37
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
PPARG P37231 6/20 0.35
PPARD Q03181 6/20 0.35
PPARA Q07869 6/20 0.35
HDAC11 Q96DB2 5/20 0.35
GPR84 Q9NQS5 4/20 0.35
TLR2 O60603 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
FABP4 P15090 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3736370 0.94 TSHR (0.36) ALDH1A1HSPD1BLMHSPE1LMNA
SCHEMBL4402455 0.94 HSPD1 (0.40) ALDH1A1HSPD1BLMHSPE1TSHR
1,4-Butanediol SCHEMBL3731858 0.93 ACHE (0.39) ALDH1A1LMNATSHRMEN1KMT2A
SCHEMBL8507314 0.92 HSPD1 (0.42) ALDH1A1HSPD1BLMHSPE1TSHR
SCHEMBL9809582 0.92 HSPD1 (0.42) ALDH1A1HSPD1BLMHSPE1TSHR
SCHEMBL2488203 0.92 HSPD1 (0.42) ALDH1A1HSPD1BLMHSPE1TSHR
SCHEMBL9513981 0.92 HSPD1 (0.42) ALDH1A1HSPD1BLMHSPE1TSHR
SCHEMBL3223653 0.92 HSPD1 (0.42) ALDH1A1HSPD1BLMHSPE1TSHR
SCHEMBL8505820 0.92 HSPD1 (0.42) ALDH1A1HSPD1BLMHSPE1TSHR
SCHEMBL9513723 0.92 HSPD1 (0.42) ALDH1A1HSPD1BLMHSPE1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110151363-A1 UNDERCOAT LAYER AND IMAGING MEMBERS COMPRISING SAME XEROX CORPORATION (US) 2011-06-23 US claimed
EP-0382058-A2 Process of simultaneously applying multiple layers of hydrophilic colloidal aqueous compositions to a hydrophobic support and multilayer photographic material MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-08-16 EP claimed
EP-0211991-A1 Substained release tablets and method for preparation thereof AB LEO (SE) 1987-03-04 EP claimed
US-4572740-A Citric acid esters as blowing and nucleating agents in the processing plastics BOEHRINGER INGELHEIM KG (DE) 1986-02-25 US claimed
WO-2024129811-A1 SOFTGEL CAPSULES AND A METHOD FOR PREPARING THE SOFTGEL CAPSULES R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-06-20 WO disclosed
EP-3169721-B1 SILICONE LIGANDS FOR QUANTUM DOTS NANOSYS INC (US) 2019-10-09 EP disclosed
US-9550868-B2 Pigment masterbatch INNOSOLIDS B.V. (NL) 2017-01-24 US disclosed
US-20160208059-A1 PIGMENT MASTERBATCH AMPACET CORPORATION 2016-07-21 US disclosed
US-20160017099-A1 Silicone Ligands for Quantum Dots SHOEI CHEMICAL INC. (JP) 2016-01-21 US disclosed
US-9133394-B2 Polyhedral oligomeric silsesquioxane nanocrystal stabilization ligands NANOSYS, INC. (US) 2015-09-15 US disclosed
WO-2014159936-A1 POLYHEDRAL OLIGOMERIC SILSESQUIOXANE NANOCRYSTAL STABILIZATION LIGANDS NANOSYS, INC. (US) 2014-10-02 WO disclosed
US-20140275598-A1 POLYHEDRAL OLIGOMERIC SILSESQUIOXANE NANOCRYSTAL STABILIZATION LIGANDS NANOSYS, INC. (US) 2014-09-18 US disclosed
WO-2013022345-A1 SUGAR-BASED PLASTICIZERS Koninklijke Coöperatie Cosun U.A. (NL) 2013-02-14 WO disclosed
US-8168741-B2 Chelating silicon-based polymers JOINT INTELLECTUAL PROPERTY POLICY OF MCMASTER UNIVERSITY (CA) 2012-05-01 US disclosed
US-20090118456-A1 CHELATING SILICON-BASED POLYMERS MCMASTER UNIVERSITY (CA) 2009-05-07 US disclosed
US-5225107-A Monosodium citrate, sodium bicarbonate and talc for foam control BOEHRINGER INGELHEIM GMBH (DE) 1993-07-06 US disclosed
US-4572740-A Citric acid esters as blowing and nucleating agents in the processing plastics BOEHRINGER INGELHEIM KG (DE) 1986-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118456-A1 CHELATING SILICON-BASED POLYMERS SRM, SMURF1, SLC39A14 ALDH1A1 4478/4885HSPD1 1843/4885BLM 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.