Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746804 | 0.84 | AR (0.50) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL435768 | 0.82 | TRPV4 (0.56) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL10088459 | 0.81 | MRGPRX4 (0.47) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL23588252 | 0.80 | CSNK2A1 (0.55) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL1964742 | 0.78 | AR (0.54) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL3747216 | 0.78 | GLA (0.52) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL14763362 | 0.78 | MRGPRX4 (0.47) | ARMRGPRX4FFAR1 | |
| SCHEMBL6689540 | 0.78 | NPSR1 (0.55) | MRGPRX4ALDH1A1MAPK1 | |
| SCHEMBL3751204 | 0.77 | AR (0.49) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL1964745 | 0.77 | MRGPRX4 (0.49) | ARMRGPRX4SLC6A4KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |