Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964742 | 0.86 | AR (0.54) | ARSLC6A4KCNH2SLC6A3FFAR1 | |
| SCHEMBL3744815 | 0.84 | AR (0.46) | ARSLC6A4KCNH2SLC6A3FFAR1 | |
| SCHEMBL1963697 | 0.83 | AR (0.54) | ARSLC6A4KCNH2SLC6A3FFAR1 | |
| SCHEMBL4636594 | 0.82 | AR (0.51) | ARSLC6A4KCNH2SLC6A3FFAR1 | |
| SCHEMBL27938680 | 0.81 | NR3C1 (0.43) | FFAR1NR3C1TRPV4ICMT | |
| SCHEMBL4636598 | 0.79 | AR (0.50) | ARSLC6A4KCNH2SLC6A3FFAR1 | |
| SCHEMBL31432137 | 0.78 | TRPV4 (0.38) | ARMEN1KMT2ATRPV4SLC2A1 | |
| SCHEMBL27642753 | 0.78 | CTSS (0.44) | ARMRGPRX4TRPV4 | |
| SCHEMBL3495657 | 0.78 | CTSS (0.44) | ARMRGPRX4TRPV4 | |
| SCHEMBL3743038 | 0.77 | AR (0.48) | ARSLC6A4KCNH2SLC6A3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |