Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734536 | 0.84 | AR (0.48) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL3739646 | 0.84 | AR (0.48) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL10088459 | 0.84 | MRGPRX4 (0.47) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL2344031 | 0.82 | XDH (0.53) | XDH | |
| SCHEMBL31019133 | 0.82 | XDH (0.53) | XDH | |
| SCHEMBL12455378 | 0.82 | MRGPRX4 (0.48) | ARMRGPRX4KCNH2ICMTALDH1A1 | |
| SCHEMBL435768 | 0.81 | TRPV4 (0.56) | ARMRGPRX4SLC6A4KCNH2SLC6A3 | |
| SCHEMBL28291444 | 0.81 | ALDH1A1 (0.45) | SLC6A4KCNH2SLC6A3ALDH1A1GAA | |
| SCHEMBL17309854 | 0.81 | SLC6A9 (0.47) | ARKCNH2ICMTALDH1A1GAA | |
| SCHEMBL2636175 | 0.81 | ALDH1A1 (0.42) | ARKCNH2ALDH1A1GAAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |
| US-20080280876-A1 | Novel oxadiazole compounds | ABBVIE INC. | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280876-A1 | Novel oxadiazole compounds | S1PR3, S1PR1, S1PR2 | AR 2563/4885MRGPRX4 41/4885SLC6A4 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.