Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739735 | 1.00 | KIF11 (0.42) | KIF11USP30RIPK1FADS1ABHD6 | |
| SCHEMBL3746487 | 0.88 | NOTUM (0.39) | KIF11USP30RIPK1FADS1ABHD6 | |
| SCHEMBL3746483 | 0.88 | NOTUM (0.39) | KIF11USP30RIPK1FADS1ABHD6 | |
| SCHEMBL3750856 | 0.88 | ABHD6 (0.36) | USP30RIPK1FADS1ABHD6 | |
| SCHEMBL3749810 | 0.82 | RORC (0.42) | ABHD6 | |
| SCHEMBL3749807 | 0.82 | RORC (0.42) | ABHD6 | |
| SCHEMBL3703663 | 0.79 | SLC6A2 (0.40) | — | |
| SCHEMBL3753480 | 0.79 | SLC6A2 (0.40) | — | |
| SCHEMBL3706185 | 0.79 | SLC6A2 (0.40) | — | |
| SCHEMBL3745628 | 0.77 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132015-A1 | NEW COMPOUNDS MODULATING GAMMA-SECRETASE AND THEIR USE IN THE TREATMENT OF ALPHA BETA RELATED PATHOLOGIES, SUCH AS ALZHEIMER'S DISEASE | ASTRAZENECA AB (SE) | 2010-11-18 | — | — | WO | disclosed |
| US-20100292210-A1 | Novel Compounds for A-Beta-Related Pathologies | ASTRAZENECA AB (SE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292210-A1 | Novel Compounds for A-Beta-Related Pathologies | BACE1, APP, BACE2 | KIF11 4587/4885USP30 2817/4885RIPK1 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.