Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1418639 | 0.83 | L3MBTL1 (0.39) | L3MBTL1LMNATSHRALDH1A1 | |
| SCHEMBL5113729 | 0.79 | GPR84 (0.30) | — | |
| SCHEMBL9539306 | 0.78 | — | — | |
| SCHEMBL7401426 | 0.76 | — | — | |
| SCHEMBL6542191 | 0.76 | — | — | |
| SCHEMBL11239022 | 0.75 | — | — | |
| SCHEMBL18203168 | 0.74 | — | — | |
| SCHEMBL11036915 | 0.72 | POLB (0.41) | L3MBTL1LMNAPLA2G4BALDH1A1 | |
| SCHEMBL5255463 | 0.72 | — | — | |
| SCHEMBL4683951 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280113-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2010-11-04 | — | — | US | claimed |
| US-20050032646-A1 | Agents for the regulation of gametophytic self-incompatibility and a control method for the breakdown of gametophytic self-incompatibility using the agents | BICBIO CO. LTD. (KR) | 2005-02-10 | — | — | US | disclosed |
| WO-2004036997-A1 | AGENTS FOR THE REGULATION OF GAMETOPHYTIC SELF-INCOMPATIBILITY AND A CONTROL METHOD FOR THE BREAKDOWN OF GAMETOPHYTIC SELF-INCOMPATIBILITY USING THE AGENTS | BICBIO CO., LTD (KR) | 2004-05-06 | — | — | WO | disclosed |
| EP-0395251-A1 | Herbicidal sulfonamides | ICI AUSTRALIA LIMITED (AU) | 1990-10-31 | — | — | EP | disclosed |