⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255463 | 0.85 | — | — | |
| SCHEMBL7401426 | 0.81 | — | — | |
| SCHEMBL3740249 | 0.76 | L3MBTL1 (0.40) | — | |
| SCHEMBL3295477 | 0.76 | — | — | |
| SCHEMBL6542803 | 0.74 | — | — | |
| SCHEMBL9539306 | 0.74 | — | — | |
| SCHEMBL496727 | 0.73 | — | — | |
| SCHEMBL4683951 | 0.73 | — | — | |
| SCHEMBL4263074 | 0.73 | — | — | |
| SCHEMBL5113729 | 0.72 | GPR84 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223809-A4 | METHODS OF TREATING HAIR LOSS COMPRISING ADMINISTERING INDOLINE COMPOUND | UNIV TEXAS SOUTHWESTERN MED CT (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223809-A1 | METHODS OF TREATING HAIR LOSS COMPRISING ADMINISTERING INDOLINE COMPOUND | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030151-A1 | METHODS OF TREATING HAIR LOSS COMPRISING ADMINISTERING INDOLINE COMPOUND | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2001-05-03 | — | — | WO | disclosed |