SCHEMBL3740437

SCHEMBL3740437

Brc1ccc(-c2ccccc2N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
MAPK1 P28482 3/20 0.46
TDP1 Q9NUW8 3/20 0.37
PTPRC P08575 1/20 0.37
SLC6A3 Q01959 1/20 0.37
NPC1 O15118 5/20 0.35
RAB9A P51151 4/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
MAPT P10636 3/20 0.35
TSHR P16473 3/20 0.35
HPGD P15428 2/20 0.35
TP53 P04637 1/20 0.35
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17700993 0.95 ALDH1A1 (0.52) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL18859311 0.94 ALDH1A1 (0.45) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL8577005 0.94 ALDH1A1 (0.43) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL15662355 0.93 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL4608172 0.93 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL15662815 0.93 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL16577756 0.93 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL15525343 0.92 ALDH1A1 (0.46) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL5918737 0.89 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1PTPRCSLC6A3
SCHEMBL66251 0.89 ALDH1A1 (0.54) ALDH1A1MAPK1TDP1PTPRCSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105348432-B One birdss of the same feather flock together compound type sulfosalt class photo-acid agent, preparation method and applications 同济大学 2017-07-11 CN claimed
CN-105348432-A Polymer type sulfonium salt photo-acid generator, and preparation method and application thereof UNIV TONGJI 2016-02-24 CN claimed
CN-104181772-A Two-photon active photoacid generators taking biphenyl as conjugated structure and preparation method and application of two-photon active photoacid generators UNIV TONGJI 2014-12-03 CN claimed
CN-104181772-B Two-photon activity photo-acid agent of the one kind using biphenyl as conjugated structure, preparation method and applications 同济大学 2018-07-03 CN disclosed
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-05 US disclosed
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-05 US disclosed
CN-105348432-B One birdss of the same feather flock together compound type sulfosalt class photo-acid agent, preparation method and applications 同济大学 2017-07-11 CN disclosed
CN-105348432-A Polymer type sulfonium salt photo-acid generator, and preparation method and application thereof UNIV TONGJI 2016-02-24 CN disclosed
CN-104181772-A Two-photon active photoacid generators taking biphenyl as conjugated structure and preparation method and application of two-photon active photoacid generators UNIV TONGJI 2014-12-03 CN disclosed
EP-1976822-B1 Compositions comprising aromatic amines and electronic devices made with such compositions DU PONT (US) 2014-04-23 EP disclosed
CN-102026957-A Triarylamine derivative, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LAB 2011-04-20 CN disclosed
US-7838627-B2 Compositions comprising novel compounds and polymers, and electronic devices made with such compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-23 US disclosed
EP-1976822-A2 COMPOSITIONS COMPRISING NOVEL COMPOUNDS AND ELECTRONIC DEVICES MADE WITH SUCH COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-10-08 EP disclosed
US-20070232782-A1 charge transport compounds for use in organic light emitting diodes; polyamine electroconductive polymer contains monomeric unit derived from the charge transport compound; photoactive; electroluminescence; energy efficiency LG CHEM, LTD. (KR) 2007-10-04 US disclosed
WO-2007079101-A2 COMPOSITIONS COMPRISING NOVEL COMPOUNDS AND ELECTRONIC DEVICES MADE WITH SUCH COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232782-A1 charge transport compounds for use in organic light emitting diodes; polyamine electroconductive polymer contains monomeric unit derived from the charge transport compound; photoactive; electroluminescence; energy efficiency SLC1A1, SLC7A5, SLC1A2 ALDH1A1 1086/4885MAPK1 2073/4885TDP1 2011/4885
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF OCIAD1, GPX1, PIEZO1 ALDH1A1 453/4885MAPK1 258/4885TDP1 1456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.