SCHEMBL37406

SCHEMBL37406

Nc1nc(=O)c2ncn(C3OC(COP(=O)(O)OP(=O)(O)O)C(O)C3O)c2[nH]1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.62
P2RY1 P47900 6/20 0.60
ENPP1 P22413 2/20 0.60
P2RY12 Q9H244 1/20 0.60
P2RX3 P56373 4/20 0.59
P2RX1 P51575 2/20 0.59
P2RX4 Q99571 2/20 0.59
P2RY6 Q15077 2/20 0.59
P2RY11 Q96G91 1/20 0.59
P2RY2 P41231 3/20 0.58
P2RX2 Q9UBL9 2/20 0.58
SRC P12931 1/20 0.58
ALDH1A1 P00352 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
NT5E P21589 1/20 0.57
KRAS P01116 2/20 0.56
RNASEL Q05823 2/20 0.56
FUT5 Q11128 1/20 0.56
P2RY4 P51582 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4366674 1.00 TGM2 (0.62) TGM2P2RY1ENPP1P2RY12P2RX3
SCHEMBL4366717 1.00 TGM2 (0.62) TGM2P2RY1ENPP1P2RY12P2RX3
Guanosine Triphosphate SCHEMBL4362831 0.98 TGM2 (0.62) TGM2P2RY1ENPP1P2RY12P2RX3
Gtp SCHEMBL4368666 0.98 TGM2 (0.62) TGM2P2RY1ENPP1P2RY12P2RX3
Gtp SCHEMBL4362801 0.98 TGM2 (0.62) TGM2P2RY1ENPP1P2RY12P2RX3
Guanosine Triphosphate SCHEMBL44409 0.98 TGM2 (0.62) TGM2P2RY1ENPP1P2RY12P2RX3
Guanosine Triphosphate SCHEMBL20266272 0.97 TGM2 (0.62) TGM2P2RY1ENPP1P2RY12P2RX3
SCHEMBL4362564 0.95 TGM2 (0.65) TGM2P2RY1ENPP1P2RX3P2RX1
SCHEMBL4357900 0.95 TGM2 (0.65) TGM2P2RY1ENPP1P2RX3P2RX1
SCHEMBL18661219 0.95 TGM2 (0.65) TGM2P2RY1ENPP1P2RX3P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7191 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
WO-2026103681-A1 PROTEIN-GLYCAN CONJUGATE HAVING MULTIPLE PAYLOADS 江苏康宁杰瑞生物制药有限公司 2026-05-21 WO claimed
WO-2026103680-A1 BISPECIFIC ANTIBODY-MULTIPLE-PAYLOAD CONJUGATE 江苏康宁杰瑞生物制药有限公司 2026-05-21 WO claimed
US-12624375-B2 Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates NORTHWESTERN UNIVERSITY (US) 2026-05-12 US claimed
US-12605434-B2 Composition for preventing or treating autoimmune diseases STATENS SERUM INSTITUT (DK) 2026-04-21 US claimed
US-20260076917-A1 COMPOSITION AND PROCESS FOR A LIPID NANO-PARTICLE DELIVERY OF OXYGEN AND VITAL METABOLIC COMPOUNDS FOR HEMORRHAGIC SHOCK KALOCYTE INC (US) 2026-03-19 US claimed
US-20260063623-A1 METHODS OF ASSESSING METABOLIC FLUX UNIV MICHIGAN REGENTS (US) 2026-03-05 US claimed
US-20260009062-A1 TRANSFER OF C2'-EPIMERIZED SUGARS TO THE AMPHOTERICIN B AGLYCONE UNIV ILLINOIS (US) 2026-01-08 US claimed
EP-2911699-B2 MODIFIED ANTIBODY, ANTIBODY-CONJUGATE AND PROCESS FOR THE PREPARATION THEREOF SYNAFFIX BV (NL) 2025-09-10 EP claimed
EP-4608984-A2 ENZYMATICALLY MEDIATED REACTIVE CRYSTALLIZATION OF STEVIOL GLYCOSIDES Arzeda Corp. (US) 2025-09-03 EP claimed
EP-0540687-A4 ANTIBODY-MEDIATED COFACTOR-DRIVEN REACTIONS 1993-10-13 EP claimed
EP-0540687-A1 ANTIBODY-MEDIATED COFACTOR-DRIVEN REACTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-05-12 EP claimed
WO-1992019632-A1 TRIFLUOROMETHYL ANALOGS OF FUCOSE AND USES THEREOF THE BIOMEMBRANE INSTITUTE (US) 1992-11-12 WO claimed
EP-0497870-A4 ENZYME ASSAY AND ASSAY KIT TO MEASURE CELLULAR ACTIVATION 1992-09-16 EP claimed
EP-0497870-A1 ENZYME ASSAY AND ASSAY KIT TO MEASURE CELLULAR ACTIVATION JAFFE, Russell M. (US) 1992-08-12 EP claimed
WO-1992001781-A1 ANTIBODY-MEDIATED COFACTOR-DRIVEN REACTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-02-06 WO claimed
CN-1051791-A Enzyme assay and assay kit for measuring cell activation RUSSELL M JAFEE (US) 1991-05-29 CN claimed
WO-1991006859-A1 ENZYME ASSAY AND ASSAY KIT TO MEASURE CELLULAR ACTIVATION JAFFE RUSSELL M (US) 1991-05-16 WO claimed
US-4826824-A Method of enhancing the taste perception of sweetness of aspartame and derivatives thereof DUKE UNIVERSITY (US) 1989-05-02 US claimed
US-4318980-A Heterogenous specific binding assay employing a cycling reactant as label MILES LABORATORIES, INC. (US) 1982-03-09 US claimed