Guanosine Triphosphate

Guanosine Triphosphate

SCHEMBL44409

Nc1nc(=O)c2ncn([C@@H]3O[C@H](CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O)c2[nH]1

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.62
P2RX3 P56373 4/20 0.62
P2RY1 P47900 5/20 0.62
ENPP1 P22413 2/20 0.62
P2RX1 P51575 2/20 0.62
P2RX4 Q99571 2/20 0.62
P2RY6 Q15077 2/20 0.62
P2RY11 Q96G91 1/20 0.62
P2RY2 P41231 3/20 0.61
P2RX2 Q9UBL9 2/20 0.61
SRC P12931 1/20 0.61
ALDH1A1 P00352 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
P2RY12 Q9H244 1/20 0.61
KRAS P01116 2/20 0.59
RNASEL Q05823 2/20 0.59
FUT5 Q11128 1/20 0.58
NT5E P21589 1/20 0.58
P2RY4 P51582 1/20 0.57
MACROD2 A1Z1Q3 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gtp SCHEMBL4368666 1.00 TGM2 (0.62) TGM2P2RX3P2RY1ENPP1P2RX1
Guanosine Triphosphate SCHEMBL4362831 1.00 TGM2 (0.62) TGM2P2RX3P2RY1ENPP1P2RX1
Gtp SCHEMBL4362801 1.00 TGM2 (0.62) TGM2P2RX3P2RY1ENPP1P2RX1
Guanosine Triphosphate SCHEMBL20266272 0.99 TGM2 (0.62) TGM2P2RX3P2RY1ENPP1P2RX1
SCHEMBL4366717 0.98 TGM2 (0.62) TGM2P2RX3P2RY1ENPP1P2RX1
SCHEMBL37406 0.98 TGM2 (0.62) TGM2P2RX3P2RY1ENPP1P2RX1
SCHEMBL4366674 0.98 TGM2 (0.62) TGM2P2RX3P2RY1ENPP1P2RX1
SCHEMBL4357900 0.97 TGM2 (0.65) TGM2P2RX3P2RY1ENPP1P2RX1
SCHEMBL18661219 0.97 TGM2 (0.65) TGM2P2RX3P2RY1ENPP1P2RX1
SCHEMBL4362564 0.97 TGM2 (0.65) TGM2P2RX3P2RY1ENPP1P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15695 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
WO-2026099317-A2 SINGLE-POT IN VITRO TRANSCRIPTION OF SYNTHETIC CAPPED MRNA ANEMOCYTE S.R.L. (IT) 2026-05-15 WO claimed
WO-2026098772-A1 SINGLE-POT IN VITRO TRANSCRIPTION OF SYNTHETIC CAPPED MRNA ANEMOCYTE S.R.L. (IT) 2026-05-15 WO claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260117271-A1 SPECTRAL MONITORING OF IN VITRO TRANSCRIPTION SANOFI PASTEUR INC (US) 2026-04-30 US claimed
EP-4722361-A1 VECTOR USED FOR PREPARING CIRCULAR RNA AND METHOD Nanjing GenScript Biotech Co., Ltd. (CN) 2026-04-08 EP claimed
US-20260076917-A1 COMPOSITION AND PROCESS FOR A LIPID NANO-PARTICLE DELIVERY OF OXYGEN AND VITAL METABOLIC COMPOUNDS FOR HEMORRHAGIC SHOCK KALOCYTE INC (US) 2026-03-19 US claimed
US-20260072030-A1 RAS BIOSENSORS UNIV CALIFORNIA (US) 2026-03-12 US claimed
US-20260062439-A1 Enzymatic RNA Capping Method NEW ENGLAND BIOLABS, INC. (US) 2026-03-05 US claimed
US-20260062438-A1 Enzymatic RNA Capping Method NEW ENGLAND BIOLABS, INC. (US) 2026-03-05 US claimed
WO-1991014699-A1 SITE SPECIFIC CLEAVAGE OF SINGLE-STRANDED DNA THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) 1991-10-03 WO claimed
WO-1990010234-A1 METHOD AND KIT FOR DETERMINING TYROSINE-PHOSPHORYLATING AND DEPHOSPHORYLATING ACTIVITIES EURO-DIAGNOSTICS B.V. (NL) 1990-09-07 WO claimed
US-4826824-A Method of enhancing the taste perception of sweetness of aspartame and derivatives thereof DUKE UNIVERSITY (US) 1989-05-02 US claimed
US-4806415-A COLORIMETRIC ANALYSIS OF GENERATED ENZYME MILES INC. (US) 1989-02-21 US claimed
US-4575498-A 5-AMINO-4-IMIDAZOLE CARBOXAMIDE RIBOSIDE DUKE UNIVERSITY (US) 1986-03-11 US claimed
EP-0073628-B1 LIGHT-SENSITIVE COMPOSITIONS USING RHODOPSIN AND LIGHT-ACTIVATABLE ENZYMES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-02-20 EP claimed
EP-0073628-A1 Light-sensitive compositions using rhodopsin and light-activatable enzymes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-03-09 EP claimed
US-4356256-A Photographic compositions, elements and processes using light-activatable enzymes EASTMAN KODAK CO. (US) 1982-10-26 US claimed
US-4318980-A Heterogenous specific binding assay employing a cycling reactant as label MILES LABORATORIES, INC. (US) 1982-03-09 US claimed
US-4046879-A TOPICAL BOEHRINGER INGELHEIM GMBH (DT) 1977-09-06 US claimed