Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066483 | 0.88 | HCAR2 (0.32) | ATMALDH1A1HCAR2TSHR | |
| SCHEMBL10779846 | 0.82 | ALDH1A1 (0.40) | ATMALDH1A1HCAR2TSHRHPGD | |
| SCHEMBL15066109 | 0.79 | CYP4F2 (0.38) | ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL22960242 | 0.78 | ATM (0.48) | ATMALDH1A1HCAR2TSHRHPGD | |
| SCHEMBL9649662 | 0.77 | ALDH1A1 (0.48) | ATMALDH1A1HCAR2TSHRHPGD | |
| SCHEMBL22971744 | 0.76 | NAAA (0.48) | ATMALDH1A1HCAR2TSHRCYP4F2 | |
| SCHEMBL1357851 | 0.74 | NAAA (0.52) | ATMALDH1A1HCAR2TSHRNPSR1 | |
| SCHEMBL11374293 | 0.74 | CYP4F2 (0.51) | ATMALDH1A1HCAR2TSHRCYP4F2 | |
| SCHEMBL705409 | 0.71 | CYP4F2 (0.36) | ATMCYP4F2CYP4A11MAPTCES2 | |
| SCHEMBL6291594 | 0.71 | CYP4F2 (0.48) | ATMTSHRCYP4F2CYP4A11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120196225-A1 | Photo Patternable Coating Compositions of Silicones and Organic-Inorganic Hybrids | NAMITEK SPECIALTY MATERIALS CORP. (US) | 2012-08-02 | — | — | US | disclosed |
| US-20100291475-A1 | Silicone Coating Compositions | LI CHENGHONG | 2010-11-18 | — | — | US | disclosed |
| EP-1342742-B1 | Room temperature curable polysiloxane compositions | HANSE CHEMIE AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| EP-1342742-A1 | Room temperature curable polysiloxane compositions | hanse chemie AG (DE) | 2003-09-10 | — | — | EP | disclosed |