Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3741634 | 0.87 | LTB4R (0.35) | LTB4RPDE2ACNR1 | |
| SCHEMBL3738424 | 0.87 | LTB4R (0.35) | LTB4RPDE2ACNR1 | |
| SCHEMBL3745793 | 0.87 | LTB4R (0.35) | LTB4RPDE2ACNR1 | |
| SCHEMBL3735599 | 0.86 | LTB4R (0.35) | LTB4RPDE2ACNR1 | |
| SCHEMBL3732538 | 0.84 | LTB4R (0.34) | LTB4R | |
| SCHEMBL3732169 | 0.79 | RXFP1 (0.36) | TP53ALDH1A1 | |
| SCHEMBL3736494 | 0.75 | RXFP1 (0.36) | L3MBTL1ALDH1A1 | |
| SCHEMBL3742726 | 0.74 | MAOB (0.34) | LTB4RLMNA | |
| SCHEMBL3742855 | 0.72 | MAOB (0.36) | LTB4RTP53MAPK1PDE2A | |
| SCHEMBL11689249 | 0.72 | ACHE (0.36) | MAPK1L3MBTL1BACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |