⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739493 | 0.81 | ALDH1A1 (0.44) | — | |
| SCHEMBL5353984 | 0.78 | MAPT (0.33) | — | |
| SCHEMBL3747840 | 0.73 | GAA (0.44) | — | |
| SCHEMBL2211928 | 0.72 | PDPK1 (0.46) | — | |
| SCHEMBL5355939 | 0.72 | — | — | |
| SCHEMBL31151370 | 0.70 | TP53 (0.31) | — | |
| SCHEMBL395801 | 0.70 | TP53 (0.31) | — | |
| SCHEMBL8050642 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL346282 | 0.68 | — | — | |
| SCHEMBL4615662 | 0.68 | F9 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |
| US-8481810-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-09 | — | — | US | disclosed |
| US-7838732-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-23 | — | — | US | disclosed |
| WO-2009095098-A2 | USE OF BENZOTHIADIAZOLES | RWTH AACHEN (DE) | 2009-08-06 | — | — | WO | disclosed |
| US-7361806-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-22 | — | — | US | disclosed |
| US-20080078005-A1 | TRANSGENIC PLANTS EXPRESSING A CELLULASE | LEBEL EDOUARD G | 2008-03-27 | — | — | US | disclosed |
| US-20080022425-A1 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATION AG | 2008-01-24 | — | — | US | disclosed |
| US-7030294-B2 | Heterologous expression cassette of a nucleotide sequence under control of an inducible promoter | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-18 | — | — | US | disclosed |
| EP-1574580-A2 | Transgenic plants expressing cellulolytic enzymes | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| EP-0925362-B1 | TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-20 | — | — | EP | disclosed |
| US-5777200-A | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof | NOVARTIS FINANCE CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| WO-1998026082-A1 | METHODS OF USING THE NIM1 GENE TO CONFER DISEASE RESISTANCE IN PLANTS | NOVARTIS AG (CH) | 1998-06-18 | — | — | WO | disclosed |
| US-5767369-A | PLANT RESISTANCE | NOVARTIS FINANCE CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1998011235-A2 | TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES | NOVARTIS AG (CH) | 1998-03-19 | — | — | WO | disclosed |
| WO-1998003536-A1 | CHEMICALLY-INDUCIBLE ARABIDOPSIS PR-1 PROMOTER | NOVARTIS AG (CH) | 1998-01-29 | — | — | WO | disclosed |
| US-5689044-A | GENETIC ENGINEERING | NOVARTIS CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| US-5654414-A | GENETIC ENGINEERING | NOVARTIS FINANCE CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5650505-A | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof | NOVARTIS CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |
| US-5614395-A | SCREENING FOR AGROCHEMICALS HAVING THE ABILITY TO INDUCE SYSTEMIC ACQUIRED RESISTANCE IN PLANTS | CIBA-GEIGY CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | disclosed |