Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353984 | 0.70 | MAPT (0.33) | ALDH1A1LMNAMAPTHTTHSD17B10 | |
| SCHEMBL3739493 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL29527999 | 0.69 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL28754170 | 0.69 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL3743851 | 0.68 | GRM2 (0.36) | HTTHIF1ASMN1; SMN2 | |
| SCHEMBL16671658 | 0.68 | TRPA1 (0.44) | ALDH1A1LMNAMAPTHTTHIF1A | |
| SCHEMBL30546824 | 0.66 | MAPT (0.34) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL3747840 | 0.66 | GAA (0.44) | ALDH1A1MAPTPOLB | |
| SCHEMBL2914523 | 0.64 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTHTTHIF1A | |
| SCHEMBL2914526 | 0.64 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTHTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502473-B1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | NOVARTIS AG (CH) | 2000-04-26 | — | — | EP | claimed |
| US-5384321-A | Benzothiadiazole compounds | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | claimed |
| US-5260423-A | Fungicide, viricide or bactericide | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | claimed |
| EP-0502473-A1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | CIBA-GEIGY AG (CH) | 1992-09-09 | — | — | EP | claimed |
| EP-0502473-B1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | NOVARTIS AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| US-5384321-A | Benzothiadiazole compounds | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| US-5260423-A | Fungicide, viricide or bactericide | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0502473-A1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | CIBA-GEIGY AG (CH) | 1992-09-09 | — | — | EP | disclosed |