SCHEMBL37425

SCHEMBL37425

CCCCC(CC)CC(CC(CC)CCCC)(C(CC)CCCC)P(=O)(O)O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FDPS P14324 8/20 0.49
CYP3A4 P08684 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CA2 P00918 2/20 0.39
TDP1 Q9NUW8 2/20 0.37
LAP3 P28838 2/20 0.37
TSHR P16473 3/20 0.36
ATM Q13315 1/20 0.36
GGPS1 O95749 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11422915 0.85 CYP3A4 (0.43) FDPSCYP3A4L3MBTL1ALDH1A1CA2
SCHEMBL11045968 0.83 AKT1 (0.42) FDPSCYP3A4L3MBTL1ALDH1A1
SCHEMBL27744278 0.82 FDPS (0.55) FDPSLAP3GGPS1
SCHEMBL8548552 0.79 CYP3A4 (0.47) FDPSCYP3A4L3MBTL1ALDH1A1CA2
SCHEMBL2469449 0.79 CYP3A4 (0.47) FDPSCYP3A4L3MBTL1ALDH1A1CA2
SCHEMBL9929470 0.78 FDPS (0.42) FDPSCYP3A4L3MBTL1ALDH1A1CA2
SCHEMBL5548513 0.77 CYP3A4 (0.46) FDPSCYP3A4L3MBTL1ALDH1A1CA2
SCHEMBL1086791 0.76 CYP3A4 (0.42) FDPSCYP3A4L3MBTL1ALDH1A1CA2
SCHEMBL7899243 0.76 FDPS (0.53) FDPSCYP3A4L3MBTL1ALDH1A1CA2
SCHEMBL3978970 0.76 FDPS (0.61) FDPSLAP3GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10081554-B2 Use of amino-containing neutral phosphine extractant in extraction and separation of thorium and process of using same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-09-25 US claimed
US-20170267540-A1 USE OF AMINO-CONTAINING NEUTRAL PHOSPHINE EXTRACTANT IN EXTRACTION AND SEPARATION OF THORIUM AND PROCESS OF USING SAME CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2017-09-21 US claimed
US-9138003-B2 Phosphonates and derivatives thereof as enhancers of the activity of insecticides SYNGENTA CROP PROTECTION INC. (US) 2015-09-22 US claimed
US-20110098178-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2011-04-28 US claimed
EP-2079310-A2 HERBICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2009-07-22 EP claimed
EP-1509085-B1 PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES SYNGENTA LTD (GB) 2009-07-15 EP claimed
WO-2008049618-A2 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2008-05-02 WO claimed
US-20060093637-A1 Phosphonates and derivatives thereof as enhancers of the activity of insecticides ADAMA CELSIUS B.V. CURACAO 2006-05-04 US claimed
US-20050209359-A1 Use of antioxidants in radiation-curable coating compositions for producing adhesive coatings GOLDSCHMIDT AG 2005-09-22 US claimed
EP-1509085-A1 PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES Syngenta Limited (GB) 2005-03-02 EP claimed
WO-2003099012-A1 PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES SYNGENTA LIMITED (GB) 2003-12-04 WO claimed
US-4986742-A EXTRACTION OF TITANYL SULFATE WITH AN ORGANOPHOSPHORUS COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1991-01-22 US claimed
US-4964997-A DISSOLVING RESIDUE WITH NITRIC ACID, EXTRACTING WITH WATER-INSOLUBLE NEUTRAL ORGANOPHOSPHORIC EXTRACTANT RHONE-POULENC CHIMIE (FR) 1990-10-23 US claimed
US-4816496-A HEAT AND LIGHT RESISTANT ADHESIVES AND FILMS KABUSHIKI KAISHA TOSHIBA (JP) 1989-03-28 US claimed
EP-0021990-B1 PROCESS FOR TREATING MIXTURES OF RARE EARTH OXIDES AND GALLIUM OXIDES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-12-01 EP claimed
US-20240341303-A1 PLANT SURFACE PROTECTIVE COMPOSITION FOR DELAYING BUD-BREAK, METHODS OF USE AND MANUFACTURE FROSTDEFENSE ENVIROTECH, INC. 2024-10-17 US disclosed
EP-4380359-A1 PLANT SURFACE PROTECTIVE COMPOSITION FOR DELAYING BUD-BREAK, METHODS OF USE AND MANUFACTURE Frostdefense Envirotech, Inc. (US) 2024-06-12 EP disclosed
US-4816496-A HEAT AND LIGHT RESISTANT ADHESIVES AND FILMS KABUSHIKI KAISHA TOSHIBA (JP) 1989-03-28 US disclosed
EP-0207403-A2 Process for the preparation of high value titanium dioxide with sulfuric acid leaching BAYER ANTWERPEN N.V. (BE) 1987-01-07 EP disclosed
EP-0172330-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060093637-A1 Phosphonates and derivatives thereof as enhancers of the activity of insecticides PHOSPHO1, PTEN, PPIP5K2 FDPS 972/4885CYP3A4 2272/4885L3MBTL1 680/4885
US-10081554-B2 Use of amino-containing neutral phosphine extractant in extraction and separation of thorium and process of using same PHOSPHO1, PTMS, PRMT5 FDPS 2242/4885CYP3A4 4355/4885L3MBTL1 1181/4885
US-20170267540-A1 USE OF AMINO-CONTAINING NEUTRAL PHOSPHINE EXTRACTANT IN EXTRACTION AND SEPARATION OF THORIUM AND PROCESS OF USING SAME PHOSPHO1, PTMS, PRMT5 FDPS 2242/4885CYP3A4 4355/4885L3MBTL1 1181/4885
US-20240341303-A1 PLANT SURFACE PROTECTIVE COMPOSITION FOR DELAYING BUD-BREAK, METHODS OF USE AND MANUFACTURE BROX, BOLA2; BOLA2B, CNPY3 FDPS 1691/4885CYP3A4 3882/4885L3MBTL1 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.