Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336041 | 0.85 | NR4A2 (0.55) | NR4A2KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL14100100 | 0.84 | MMP2 (0.61) | NR4A2KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL30852401 | 0.84 | G6PD (0.61) | NR4A2KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL2419751 | 0.84 | G6PD (0.61) | NR4A2KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11632071 | 0.82 | KMT2A (0.47) | NR4A2KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9631839 | 0.81 | ALDH1A1 (0.43) | KMT2AKDM4EALDH1A1CYP1A2POLB | |
| SCHEMBL9629932 | 0.80 | NR4A2 (0.55) | NR4A2KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9630981 | 0.79 | ALDH1A1 (0.47) | KMT2AKDM4EALDH1A1POLBHSD17B10 | |
| SCHEMBL10582732 | 0.79 | MMP2 (0.44) | KMT2AKDM4EALDH1A1GLAHPGD | |
| SCHEMBL9631015 | 0.77 | ALDH1A1 (0.50) | KMT2AKDM4EALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841077-B2 | Biomarkers for amyotrophic lateral sclerosis and methods using the same | MASSACHUSETTS GENERAL HOSPITAL (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130309697-A1 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | MITCHELL MATTHEW W (US) | 2013-11-21 | — | — | US | disclosed |
| US-8518650-B2 | Biomarkers for prostate cancer and methods using the same | METABOLON, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-20100292331-A1 | Biomarkers for Prostate Cancer and Methods Using the Same | METABALON, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20070298998-A1 | Biomarkers for amyotrophic lateral sclerosis and methods using the same | METABOLON, INC. (US) | 2007-12-27 | — | — | US | disclosed |