Fluorosalan

Fluorosalan

SCHEMBL374268

O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Br)cc(Br)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 1.00
HTT P42858 2/20 1.00
KMT2A Q03164 2/20 1.00
OPRK1 P41145 1/20 1.00
HSPD1 P10809 2/20 0.67
HSPE1 P61604 2/20 0.67
MAOB P27338 2/20 0.64
P2RX1 P51575 2/20 0.62
RXFP1 Q9HBX9 9/20 0.61
MAPT P10636 3/20 0.60
PTGS1 P23219 2/20 0.60
ALDH1A1 P00352 1/20 0.60
EGFR P00533 1/20 0.60
LMNA P02545 1/20 0.60
ERBB2 P04626 1/20 0.60
CYP1A2 P05177 1/20 0.60
LCK P06239 1/20 0.60
CYP2C9 P11712 1/20 0.60
MAPK1 P28482 1/20 0.60
MAPK14 Q16539 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorosalan SCHEMBL30318966 1.00 MEN1 (1.00) MEN1HTTKMT2AOPRK1HSPD1
Fluorosalan SCHEMBL29484458 1.00 MEN1 (1.00) MEN1HTTKMT2AOPRK1HSPD1
Fluorosalan SCHEMBL30288529 1.00 MEN1 (1.00) MEN1HTTKMT2AOPRK1HSPD1
Fluorosalan SCHEMBL8668901 0.95 MEN1 (0.91) MEN1HTTKMT2AOPRK1HSPD1
SCHEMBL4922276 0.87 MEN1 (0.76) MEN1HTTKMT2AOPRK1HSPD1
SCHEMBL574776 0.85 MEN1 (0.74) MEN1HTTKMT2AOPRK1HSPD1
SCHEMBL331050 0.85 MEN1 (0.74) MEN1HTTKMT2AOPRK1HSPD1
SCHEMBL330388 0.83 TMPRSS4 (0.78) MEN1HTTKMT2AOPRK1P2RX1
SCHEMBL15209878 0.82 MEN1 (0.70) MEN1HTTKMT2AOPRK1MAOB
Cetylpyridinium SCHEMBL11499480 0.82 MEN1 (0.67) MEN1HTTKMT2AOPRK1HSPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 837 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025129271-A1 LIPID DELIVERY VEHICLE THE UNIVERSITY OF QUEENSLAND (AU) 2025-06-26 WO claimed
CN-113209066-B Amino-aryl-benzamide compounds and methods of use thereof 上海赫普化医药技术有限公司 2024-05-10 CN claimed
US-20210161868-A1 ANTI-INFLAMMATORY THERAPY IN ARRHYTHMOGENIC CARDIOMYOPATHY (ACM) BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2021-06-03 US claimed
US-20200325483-A1 SAFE DELIVERY OF CRISPR AND OTHER GENE THERAPIES TO LARGE FRACTIONS OF SOMATIC CELLS IN HUMANS AND ANIMALS HANLEY BRIAN P (US) 2020-10-15 US claimed
EP-3670666-A1 METHOD FOR OPTICAL IMAGING A TARGET MOLECULE IN A SAMPLE, A PROTEIN-OLIGONULEOTIDE CONJUGATE FOR USE IN THE METHOD AND A KIT FOR CARRYING OUT THE METHOD Freie Universität Berlin (DE) 2020-06-24 EP claimed
US-10377779-B2 Carbonate prodrugs and methods of using the same ACORDA THERAPEUTICS, INC. (US) 2019-08-13 US claimed
CN-109152342-A CRISPR and other gene therapies are safe to deliver to most cells in humans and animals 布赖恩.P.汉利 2019-01-04 CN claimed
US-20180086778-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME NEUROGESX, INC. 2018-03-29 US claimed
WO-2017197301-A1 SAFE DELIVERY OF CRISPR AND OTHER GENE THERAPIES TO LARGE FRACTIONS OF SOMATIC CELLS IN HUMANS AND ANIMALS HANLEY BRIAN P (US) 2017-11-16 WO claimed
WO-2016010984-A2 COMPOSITIONS AND METHODS FOR TREATING ROSACEA TISSUE TECH, INC. (US) 2016-01-21 WO claimed
US-6395697-B1 IN SOLVENT AND WATER SOLUTION RECKITT BENCKISER INC. 2002-05-28 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1071324-A1 BLOOMING TYPE GERMICIDAL HARD-SURFACE CLEANERS Reckitt Benckiser Inc. (US) 2001-01-31 EP claimed
US-6066606-A MIXTURE OF TERPENE, SURFACTANT AND WATER RECKITT & COLMAN INC. (US) 2000-05-23 US claimed
WO-1999052361-A1 BLOOMING TYPE GERMICIDAL HARD-SURFACE CLEANERS RECKITT BENCKISER INC. (US) 1999-10-21 WO claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
US-4326977-A Liquid antiseptic cleaners with improved foaming properties BASF WYANDOTTE CORPORATION (US) 1982-04-27 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4205061-A FOR PREVENTION OF PLAQUE AND ORAL DISEASES JOHNSON & JOHNSON (US) 1980-05-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10377779-B2 Carbonate prodrugs and methods of using the same CA6, CA7, CA4 MEN1 691/4885HTT 4037/4885KMT2A 2173/4885
US-20180086778-A1 CARBONATE PRODRUGS AND METHODS OF USING THE SAME CA6, CA7, CA4 MEN1 691/4885HTT 4037/4885KMT2A 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.