SCHEMBL574776

SCHEMBL574776

O=C(Nc1ccc(C(F)(F)F)cc1)c1cc(Br)cc(Br)c1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.74
HTT P42858 2/20 0.74
KMT2A Q03164 2/20 0.74
OPRK1 P41145 1/20 0.74
MAPT P10636 2/20 0.74
PTGS1 P23219 2/20 0.74
ALDH1A1 P00352 1/20 0.74
EGFR P00533 1/20 0.74
LMNA P02545 1/20 0.74
ERBB2 P04626 1/20 0.74
CYP1A2 P05177 1/20 0.74
LCK P06239 1/20 0.74
CYP2C9 P11712 1/20 0.74
MAPK1 P28482 1/20 0.74
MAPK14 Q16539 1/20 0.74
HSPD1 P10809 3/20 0.68
HSPE1 P61604 3/20 0.68
SMN1; SMN2 Q16637 1/20 0.62
TMPRSS4 Q9NRS4 3/20 0.54
P2RX1 P51575 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorosalan SCHEMBL8668901 0.92 MEN1 (0.91) MEN1HTTKMT2AOPRK1MAPT
SCHEMBL4922276 0.87 MEN1 (0.76) MEN1HTTKMT2AOPRK1MAPT
SCHEMBL11696231 0.86 TMPRSS4 (0.59) MEN1HTTKMT2AOPRK1MAPT
SCHEMBL331050 0.86 MEN1 (0.74) MEN1HTTKMT2AOPRK1MAPT
Fluorosalan SCHEMBL374268 0.85 MEN1 (1.00) MEN1HTTKMT2AOPRK1MAPT
Fluorosalan SCHEMBL29484458 0.85 MEN1 (1.00) MEN1HTTKMT2AOPRK1MAPT
Fluorosalan SCHEMBL30288529 0.85 MEN1 (1.00) MEN1HTTKMT2AOPRK1MAPT
Fluorosalan SCHEMBL30318966 0.85 MEN1 (1.00) MEN1HTTKMT2AOPRK1MAPT
Tribromsalan SCHEMBL121315 0.85 MEN1 (1.00) MEN1HTTKMT2AOPRK1MAPT
Tribromsalan SCHEMBL29392740 0.85 MEN1 (1.00) MEN1HTTKMT2AOPRK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2313026-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS Castle Beach, L.L.C. (US) 2011-04-27 EP claimed
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS Castle Beach, LLC (US) 2010-02-18 US claimed
WO-2010019680-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS HOMOLA ANDREW M (US) 2010-02-18 WO claimed
EP-0805672-B1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 2004-08-25 EP claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US claimed
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP disclosed
EP-4551195-A1 CANNABINOID LIPID PREMIXTURE Fertin Pharma A/S (DK) 2025-05-14 EP disclosed
WO-2025067622-A1 CANNABIDIOL FOR USE IN ALLEVIATING XEROSTOMIA FERTIN PHARMA A/S (DK) 2025-04-03 WO disclosed
CN-119562805-A Cannabinoid lipid premix 费尔廷制药公司 2025-03-04 CN disclosed
EP-4088716-B1 AN ORAL TABLET FOR INDUCED SALIVA GENERATION FERTIN PHARMA AS (DK) 2024-10-16 EP disclosed
CN-112153964-B Oral tablets suitable for active pharmaceutical ingredient comprising non-directly compressible sugar alcohol particles 费尔廷制药公司 2024-07-30 CN disclosed
WO-2024008261-A1 CANNABINOID LIPID PREMIXTURE FERTIN PHARMA A/S (DK) 2024-01-11 WO disclosed
US-5192530-A Solubilizer, enhancing agent to aid retention, and delivery enhancement COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5192531-A Triclosan as a water insoluble noncationic additive for dentifrices COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5188821-A ANTIBACTERIAL ANTIPLAQUE ORAL COMPOSITION MOUTHWASH OR LIQUID DENTIFRICE COLGATE-PALMOLIVE COMPANY (US) 1993-02-23 US disclosed
US-5180578-A Adhesion to oral surfaces COLGATE-PALMOLIVE COMPANY (US) 1993-01-19 US disclosed
US-5178851-A Dentifrices treatment with triclosan and carriers COLGATE-PALMOLIVE COMPANY (US) 1993-01-12 US disclosed
US-5032386-A Dentistry COLGATE-PALMOLIVE COMPANY (US) 1991-07-16 US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS LIPA, MMP7, CTSA MEN1 4098/4885HTT 2004/4885KMT2A 4226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.