Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.74 |
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 11/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922276 | 0.96 | MEN1 (0.76) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| SCHEMBL574776 | 0.86 | MEN1 (0.74) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| Fluorosalan SCHEMBL30318966 | 0.85 | MEN1 (1.00) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| Fluorosalan SCHEMBL29484458 | 0.85 | MEN1 (1.00) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| Fluorosalan SCHEMBL30288529 | 0.85 | MEN1 (1.00) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| Fluorosalan SCHEMBL374268 | 0.85 | MEN1 (1.00) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| SCHEMBL8764506 | 0.85 | MEN1 (0.66) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| SCHEMBL129638 | 0.82 | TMPRSS4 (0.90) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| Fluorosalan SCHEMBL8668901 | 0.81 | MEN1 (0.91) | MEN1KMT2AHTTOPRK1TMPRSS4 | |
| SCHEMBL3497444 | 0.79 | MEN1 (0.65) | MEN1KMT2AHTTOPRK1TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097759-B2 | Inflammatory cytokine release inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20100274051-A1 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274051-A1 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | IL1B, NFKBIA, IL1A | MEN1 4495/4885KMT2A 4486/4885HTT 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.