SCHEMBL374293

SCHEMBL374293

O=C1C=CC(=O)N1CC(Br)CBr

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.41
FAAH O00519 4/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
BLM P54132 2/20 0.41
GMNN O75496 1/20 0.41
THPO P40225 1/20 0.41
PMP22 Q01453 1/20 0.41
HPGD P15428 2/20 0.39
HSP90AA1 P07900 1/20 0.39
TLR9 Q9NR96 1/20 0.39
TP53 P04637 1/20 0.39
PKM P14618 1/20 0.39
XBP1 P17861 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
RECQL P46063 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12930410 0.72 MGLL (0.50) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL9786718 0.69
SCHEMBL11927409 0.69 MGLL (0.46) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL153302 0.69 MGLL (0.52) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL709030 0.69 MGLL (0.46) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL25246820 0.69 MGLL (0.46) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL44138 0.69 MGLL (0.46) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL26874 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL19971742 0.67 MGLL (0.44) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL4522343 0.65 MGLL (0.62) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102936383-B Brominated polymers as flame additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES INC (US) 2014-07-30 CN claimed
CN-101959954-B Brominated polymers as flame retardant additives and polymer systems containing the same DOW GLOBAL TECHNOLOGIES INC (US) 2013-03-27 CN claimed
CN-102936383-A Brominated polymers as flame additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES INC (US) 2013-02-20 CN claimed
CN-102936382-A Brominated polymers as flame additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES INC (US) 2013-02-20 CN claimed
CN-102850718-A Brominated Polymers as FR Additives and Polymer Systems Containing Same DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-02 CN claimed
US-8242183-B2 Brominated polymers as FR additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2012-08-14 US claimed
EP-2247664-B1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-06 EP claimed
EP-2410016-A2 Brominated polymers as flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-01-25 EP claimed
EP-2410014-A2 Brominated polymers as flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-01-25 EP claimed
EP-2410015-A2 Brominated polymers as flame retardant additives and polymer systems containing same Dow Global Technologies LLC (US) 2012-01-25 EP claimed
JP-2011513537-A 2011-04-28 JP claimed
US-20100317757-A1 Brominated Polymers as FR Additives and Polymer Systems Containing Same THE DOW CHEMICAL COMPANY 2010-12-16 US claimed
EP-2247664-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME Dow Global Technologies Inc. (US) 2010-11-10 EP claimed
WO-2009108453-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-09-03 WO claimed
US-10093781-B2 Foamed styrenic polymers containing a brominated styrene-butadiene copolymer and having enhanced cell size homogeneity DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-09 US disclosed
US-9663649-B2 Stabilizers for polymers containing aliphatically-bound bromine DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-30 US disclosed
US-20170058118-A1 STABILIZERS FOR POLYMERS CONTAINING ALIPHATICALLY-BOUND BROMINE DCOMCO, INC. 2017-03-02 US disclosed
WO-2010080285-A2 STABILIZERS FOR POLYMERS CONTAINING ALIPHATICALLY-BOUND BROMINE DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-15 WO disclosed
WO-2009108453-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-09-03 WO disclosed
WO-2009108453-A1 BROMINATED POLYMERS AS FLAME ADDITIVES AND POLYMER SYSTEMS CONTAINING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-09-03 WO disclosed