SCHEMBL374354

SCHEMBL374354

C[n+]1c2ccccc2c(C(=O)Oc2ccc(CCC(=O)ON3C(=O)CCC3=O)cc2)c2ccccc21.O=S(=O)([O-])F

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
HPGD P15428 2/20 0.32
HSD17B10 Q99714 1/20 0.31
CASP3 P42574 1/20 0.31
CASP7 P55210 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL12096566 0.94 PSMB8 (0.32) KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5
Trifluoromethanesulfonic Acid SCHEMBL29698948 0.94 PSMB8 (0.32) KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5
SCHEMBL7517352 0.94 LMNA (0.35) KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5
SCHEMBL4532046 0.94 KMT2A (0.37) KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5
SCHEMBL29666930 0.94 KMT2A (0.37) KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5
SCHEMBL9426644 0.90 PSMB8 (0.32) PSMB8PSMB5
Trifluoromethanesulfonic Acid SCHEMBL2225877 0.88 PSMB8 (0.32) KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5
Trifluoromethanesulfonic Acid SCHEMBL16227774 0.82 PSMB8 (0.32) ALDH1A1SMN1; SMN2PSMB8PSMB5LMNA
SCHEMBL8469537 0.82 ALDH1A1 (0.39) KMT2AALDH1A1LMNAGAAHPGD
SCHEMBL374355 0.81 PSMB8 (0.37) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39047-E1 Luminescence by reacting an acridinium ester with superoxide MITSUBISHI KAGAKU IATRON, INC. (JP) 2006-03-28 US claimed
JP-7278184-A None JP disclosed
US-10407740-B2 Oligonucleotides for use in determining the presence of Trichomonas vaginalis in a sample GEN-PROBE INCORPORATED (US) 2019-09-10 US disclosed
US-20180044739-A1 OLIGONUCLEOTIDES FOR USE IN DETERMINIING THE PRESENCE OF TRICHOMONAS VAGINALIS IN A SAMPLE BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2018-02-15 US disclosed
US-9670554-B2 Capture probes for use in detecting the presence of Trichomonas vaginalis in a sample GEN-PROBE INCORPORATED (US) 2017-06-06 US disclosed
EP-2531515-B1 PROBES FOR DETECTING THE PRESENCE OF TROCHOMONAS VAGINALIS IN A SAMPLE GEN PROBE INC (US) 2015-10-21 EP disclosed
EP-2027293-B1 METHOD OF LYSING MYCOBACTERIUM AND AMPLIFYING ITS NUCLEIC ACID GEN PROBE INC (US) 2014-11-19 EP disclosed
US-20140335519-A1 CAPTURE PROBES FOR USE IN DETECTING THE PRESENCE OF TRICHOMONAS VAGINALIS IN A SAMPLE GEN-PROBE INCORPORATED 2014-11-13 US disclosed
US-8790879-B2 Probes for detecting the presence of Trichomonas vaginalis in a sample GEN-PROBE INCORPORATED (US) 2014-07-29 US disclosed
EP-2292793-B1 Compositions, methods and kits for determining the presence of Trichomonas Vaginalis in a test sample GEN PROBE INC (US) 2013-12-04 EP disclosed
EP-0522677-B1 Method of measuring concentration of immunoreactant using electrochemiluminescence TDK CORP (JP) 1996-12-18 EP disclosed
EP-0747488-A1 Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product GEN-PROBE INCORPORATED (US) 1996-12-11 EP disclosed
EP-0747701-A1 Micelle protection assay GEN-PROBE INCORPORATED (US) 1996-12-11 EP disclosed
EP-0722087-A1 MEASUREMENT SYSTEM USING WHOLE BLOOD IATRON LABORATORIES, INC. (JP) 1996-07-17 EP disclosed
EP-0478626-B1 DETECTING OR QUANTIFYING MULTIPLE ANALYTES USING LABELLING TECHNIQUES GEN PROBE INC (US) 1996-01-17 EP disclosed
JP-H07278184-A STABILIZATION OF ANTIGEN OR ANTIBODY LABELED WITH ACRIDINIUM DERIVATIVE KYOWA MEDEX CO LTD 1995-10-24 JP disclosed
EP-0522677-A1 Method of measuring concentration of immunoreactant using electrochemiluminescence TDK Corporation (JP) 1993-01-13 EP disclosed
EP-0519070-A1 METHOD OF JUDGING TYPE OF HUMAN LEUKOCYTE ANTIGEN Chugai Seiyaku Kabushiki Kaisha (JP) 1992-12-23 EP disclosed
EP-0478626-A1 DETECTING OR QUANTIFYING MULTIPLE ANALYTES USING LABELLING TECHNIQUES. UNIV WALES MEDICINE (GB) 1992-04-08 EP disclosed
WO-1991000511-A1 DETECTING OR QUANTIFYING MULTIPLE ANALYTES USING LABELLING TECHNIQUES UNIVERSITY OF WALES COLLEGE OF MEDICINE (GB) 1991-01-10 WO disclosed