SCHEMBL5446013

SCHEMBL5446013

C[n+]1c2ccccc2c(C(=O)[O-])c2c(-c3ccc(CCC(=O)ON4C(=O)CCC4=O)cc3)cccc21.FC(F)F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.36
PSMB5 P28074 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6842917 0.97 PSMB8 (0.38) PSMB8PSMB5
SCHEMBL3521342 0.87 PSMB8 (0.37) PSMB8PSMB5
SCHEMBL4987145 0.87 PSMB8 (0.37) PSMB8PSMB5
SCHEMBL374355 0.87 PSMB8 (0.37) PSMB8PSMB5
Trifluoromethanesulfonic Acid SCHEMBL15049846 0.85 PSMB8 (0.36) PSMB8PSMB5
SCHEMBL3415993 0.78 PSMB8 (0.36) PSMB8PSMB5
SCHEMBL4532046 0.76 KMT2A (0.37) PSMB8PSMB5
SCHEMBL29666930 0.76 KMT2A (0.37) PSMB8PSMB5
SCHEMBL5898839 0.74 PSMB8 (0.33) PSMB8PSMB5
SCHEMBL374354 0.74 KMT2A (0.33) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070031854-A1 Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses KATSILOMETES GEORGE W 2007-02-08 US disclosed
US-20020034828-A1 NOVEL 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND THEIR PREPARATION PIERCE CHEMICAL COMPANY 2002-03-21 US disclosed
EP-1026156-A2 Novel 10, 10'-substituted-9,9'-biacridine luminescent molecules and their preparation PIERCE CHEMICAL COMPANY (US) 2000-08-09 EP disclosed