Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3704392 | 0.99 | HRH3 (0.63) | HRH3PPARGPPARDPPARAKDM4E | |
| SCHEMBL10911483 | 0.82 | HRH3 (0.59) | HRH3PPARGPPARDPPARAKDM4E | |
| SCHEMBL9836860 | 0.81 | HRH3 (0.52) | HRH3PPARGPPARDPPARAKDM4E | |
| SCHEMBL5637627 | 0.80 | HRH3 (0.58) | HRH3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL665048 | 0.80 | CA12 (0.53) | HRH3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL13281625 | 0.80 | HRH3 (0.57) | HRH3PPARGPPARDPPARAKDM4E | |
| SCHEMBL14316220 | 0.79 | HRH3 (0.64) | HRH3MAPTGAAALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL8021718 | 0.79 | KDM4E (0.53) | HRH3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL27829035 | 0.79 | SMN1; SMN2 (0.60) | HRH3PPARGPPARDPPARAKDM4E | |
| SCHEMBL5638386 | 0.78 | HRH3 (0.53) | HRH3APPMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280024-A1 | RENIN INHIBITORS | CADILA HEALTHCARE LIMITED (IN) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280024-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | HRH3 2747/4885PPARG 3699/4885PPARD 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.