Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3749402 | 0.91 | CYP2D6 (0.43) | HSD11B1ALDH1A1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3752153 | 0.88 | POLB (0.50) | HSD11B1ALDH1A1POLBHTTLMNA | |
| SCHEMBL3749180 | 0.84 | CYP2D6 (0.41) | HSD11B1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3744663 | 0.81 | HSD11B1 (0.48) | HSD11B1ALDH1A1POLBHTTLMNA | |
| SCHEMBL3744810 | 0.80 | HSD11B1 (0.54) | HSD11B1ALDH1A1POLBHTTMEN1 | |
| SCHEMBL3742454 | 0.79 | HSD11B1 (0.44) | HSD11B1ALDH1A1POLBHTTLMNA | |
| SCHEMBL3742443 | 0.79 | KMT2A (0.43) | ALDH1A1POLBHTTLMNAMEN1 | |
| SCHEMBL13081850 | 0.75 | OXTR (0.39) | ALDH1A1POLBMEN1KMT2ATSHR | |
| SCHEMBL3747454 | 0.74 | POLB (0.48) | HSD11B1ALDH1A1POLBHTTLMNA | |
| SCHEMBL3744639 | 0.71 | HSD11B1 (0.47) | HSD11B1ALDH1A1POLBHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298368-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2009061681-A2 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298368-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | HSD11B1 442/4885ALDH1A1 2555/4885POLB 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.