Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757100 | 0.88 | HSD11B1 (0.52) | HSD11B1MAPTALDH1A1POLBHTT | |
| SCHEMBL3747454 | 0.87 | POLB (0.48) | HSD11B1MAPTALDH1A1POLBHTT | |
| SCHEMBL3744641 | 0.81 | HSD11B1 (0.47) | HSD11B1MAPTCCR1ALDH1A1POLB | |
| SCHEMBL3744810 | 0.80 | HSD11B1 (0.54) | HSD11B1MAPTCCR1ALDH1A1POLB | |
| SCHEMBL3749435 | 0.77 | LMNA (0.46) | HSD11B1ALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL3742454 | 0.77 | HSD11B1 (0.44) | HSD11B1MAPTALDH1A1POLBHTT | |
| SCHEMBL3752153 | 0.75 | POLB (0.50) | HSD11B1MAPTALDH1A1POLBHTT | |
| SCHEMBL3749402 | 0.71 | CYP2D6 (0.43) | HSD11B1ALDH1A1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3744660 | 0.71 | HSD11B1 (0.49) | HSD11B1MAPTCCR1ALDH1A1POLB | |
| SCHEMBL10389175 | 0.70 | PTGS2 (0.37) | MEN1KMT2ALMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298368-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298368-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | HSD11B1 442/4885MAPT 4735/4885CCR1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.