SCHEMBL374478

SCHEMBL374478

CP(Cc1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.42
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CALM1 P0DP23 1/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
TSHR P16473 4/20 0.37
ALDH1A1 P00352 4/20 0.37
IDO1 P14902 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
TRPA1 O75762 1/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 1/20 0.36
KCNH2 Q12809 1/20 0.35
MAOB P27338 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11575583 0.98 TP53 (0.40) TP53CYP3A4TDP1CALM1ESR1
Hydrochloric Acid SCHEMBL11575591 0.98 TP53 (0.40) TP53CYP3A4TDP1CALM1ESR1
Fluoride SCHEMBL27907089 0.98 TP53 (0.40) TP53CYP3A4TDP1CALM1ESR1
SCHEMBL11130686 0.87 HTT (0.42) TP53CYP3A4TDP1TSHRALDH1A1
SCHEMBL28243205 0.85 ESR1 (0.55) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL28243204 0.85 ESR1 (0.55) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL380591 0.82 LTA4H (0.55) TP53TDP1IDO1TRPA1KDM4E
SCHEMBL10785234 0.76 CYP3A4 (0.45) TP53CYP3A4TDP1CALM1ESR1
SCHEMBL1357485 0.76 TSHR (0.48) TP53CYP3A4TDP1CALM1TSHR
SCHEMBL9441831 0.76 CYP3A4 (0.45) TP53CYP3A4TDP1CALM1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3527639-B1 A METHOD FOR BONDING A THERMOPLASTIC MATERIAL BY MICROWAVE-IRRADIATION PROIONIC GMBH (AT) 2021-09-08 EP claimed
US-11084954-B2 Method for curing an adhesive using microwave irradiation PROIONIC GMBH (AT) 2021-08-10 US claimed
EP-3527639-A1 A METHOD FOR BONDING A THERMOPLASTIC MATERIAL BY MICROWAVE-IRRADIATION proionic GmbH (AT) 2019-08-21 EP claimed
US-20190169469-A1 METHOD FOR CURING AN ADHESIVE USING MICROWAVE IRRADIATION PROIONIC GMBH (AT) 2019-06-06 US claimed
US-20170015871-A1 METHOD FOR CURING AN ADHESIVE USING MICROWAVE IRRADIATION PROIONIC GMBH (AT) 2017-01-19 US claimed
EP-2997106-A1 METHOD FOR CURING AN ADHESIVE USING MICROWAVE IRRADIATION VTU Holding GmbH (AT) 2016-03-23 EP claimed
WO-2015079028-A1 METHOD FOR CURING AN ADHESIVE USING MICROWAVE IRRADIATION VTU HOLDING GMBH (AT) 2015-06-04 WO claimed
EP-1299342-B1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SANOL ARZNEI SCHWARZ GMBH (DE) 2007-05-02 EP claimed
CN-1269793-C Process for producing 3, 3-diarylpropylamines SANOL ARZNEI SCHWARZ GMBH (DE) 2006-08-16 CN claimed
US-6809225-B2 BY HYDROCARBONYLATION/HYDROFORMYLATION WITH SUBSEQUENT REDUCTIVE AMINATION SCHWARZ PHARMA AG (DE) 2004-10-26 US claimed
US-20040034080-A1 Method for producing 3,3-diarylpropylamines UCB PHARMA GMBH (DE) 2004-02-19 US claimed
CN-1441771-A Process for producing 3, 3-diarylpropylamines SANOL ARZNEI SCHWARZ GMBH (DE) 2003-09-10 CN claimed
EP-1299342-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2003-04-09 EP claimed
WO-2002004399-A1 METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2002-01-17 WO claimed
CN-115667933-A Reagent for mass spectrometry 豪夫迈·罗氏有限公司 2023-01-31 CN disclosed
EP-3527639-B1 A METHOD FOR BONDING A THERMOPLASTIC MATERIAL BY MICROWAVE-IRRADIATION PROIONIC GMBH (AT) 2021-09-08 EP disclosed
US-11084954-B2 Method for curing an adhesive using microwave irradiation PROIONIC GMBH (AT) 2021-08-10 US disclosed
US-4125540-A WITH ORGANO-PHOSPHORUS COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1978-11-14 US disclosed
US-4087411-A TRIOXANE, BORON FLUORIDE-TYPE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1978-05-02 US disclosed
US-4069243-A Preparation of trifluoromethylthioacetic acid and its esters SMITHKLINE CORPORATION (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040034080-A1 Method for producing 3,3-diarylpropylamines HNMT, CYP1A1, HRH3 TP53 3909/4885CYP3A4 66/4885TDP1 2037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.