SCHEMBL9952233

SCHEMBL9952233

Oc1c(Cc2ccccc2)ccc2[nH]nnc12

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.43
BCL2 P10415 1/20 0.41
BCL2L1 Q07817 1/20 0.41
ELANE P08246 2/20 0.40
ALOX5 P09917 1/20 0.40
CTSG P08311 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3744873 0.80 SMN1; SMN2 (0.37) PAX8BCL2BCL2L1ALOX5
Phenol SCHEMBL28088044 0.79 KEAP1 (0.40) PAX8BCL2BCL2L1ALOX5
SCHEMBL30933259 0.79 CYP3A4 (0.43) BCL2BCL2L1
SCHEMBL18393343 0.79 CYP3A4 (0.43) BCL2BCL2L1
SCHEMBL10797942 0.78 GRIN2B (0.42) PAX8BCL2BCL2L1
SCHEMBL6052202 0.76 ALDH1A1 (0.39)
SCHEMBL574848 0.76 HTR2C (0.36)
SCHEMBL9172424 0.75 ALDH1A1 (0.38)
SCHEMBL3457711 0.73 GABRA1 (0.42) ELANE
SCHEMBL3878066 0.73 BCL2 (0.39) BCL2BCL2L1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655527-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS ALLNEX AUSTRIA GmbH (AT) 2013-10-30 EP claimed
WO-2012085016-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2012-06-28 WO claimed
EP-2655527-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS ALLNEX AUSTRIA GmbH (AT) 2013-10-30 EP disclosed
WO-2012085016-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2012-06-28 WO disclosed