Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355569 | 0.82 | BTK (0.39) | RXFP1PDGFRBHSD17B10MEN1KMT2A | |
| SCHEMBL5384651 | 0.81 | RXFP1 (0.37) | RXFP1OPRK1PDGFRBPDGFRAHRH3 | |
| SCHEMBL3735042 | 0.80 | RXFP1 (0.42) | RXFP1PDGFRBPDGFRAHRH3CYP1A2 | |
| SCHEMBL3741505 | 0.77 | LTB4R (0.32) | — | |
| SCHEMBL11324116 | 0.76 | RXFP1 (0.36) | RXFP1HRH3TP53POLB | |
| SCHEMBL11056896 | 0.69 | PDE3B (0.38) | RXFP1OPRK1MEN1KMT2AHRH3 | |
| SCHEMBL11319351 | 0.67 | ESR1 (0.43) | HSD17B10KMT2ATP53MAPTCYP1A2 | |
| SCHEMBL8049856 | 0.67 | NPC1 (0.37) | PDGFRBMEN1KMT2ATP53MAPT | |
| SCHEMBL3732169 | 0.66 | RXFP1 (0.36) | RXFP1ELANETSHRHSD17B10MEN1 | |
| SCHEMBL3859298 | 0.63 | NPC1 (0.41) | RXFP1PDGFRBHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |