Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056896 | 0.89 | PDE3B (0.38) | RXFP1HRH3HTR3AHRH4KDM4E | |
| SCHEMBL5384651 | 0.84 | RXFP1 (0.37) | RXFP1HRH3HTR3AHTR3EHTR3B | |
| SCHEMBL11324116 | 0.82 | RXFP1 (0.36) | RXFP1HRH3POLBNPC1RAB9A | |
| SCHEMBL3735368 | 0.81 | RAB9A (0.45) | RXFP1CYP2C19NPC1RAB9AKDM4E | |
| SCHEMBL3745442 | 0.80 | RXFP1 (0.36) | RXFP1HRH3CYP1A2POLBCYP2C19 | |
| SCHEMBL11058817 | 0.80 | BACE1 (0.36) | HRH3KDM4E | |
| SCHEMBL11059611 | 0.74 | RXFP1 (0.39) | RXFP1NR4A2NPC1RAB9AKDM4E | |
| SCHEMBL3741505 | 0.70 | LTB4R (0.32) | — | |
| SCHEMBL3736494 | 0.69 | RXFP1 (0.36) | RXFP1HRH3HTR3AHTR3EHTR3B | |
| SCHEMBL5382968 | 0.68 | RXFP1 (0.38) | RXFP1HRH3HTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |