Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735042 | 0.89 | RXFP1 (0.42) | HRH3RXFP1HTR3AHRH4KDM4E | |
| SCHEMBL3735368 | 0.81 | RAB9A (0.45) | PDE3BPDE3ARXFP1KDM4EMEN1 | |
| SCHEMBL5384651 | 0.72 | RXFP1 (0.37) | HRH3RXFP1HTR3AOPRK1 | |
| SCHEMBL11324116 | 0.71 | RXFP1 (0.36) | HRH3RXFP1TDP1HTTL3MBTL1 | |
| SCHEMBL11058817 | 0.71 | BACE1 (0.36) | HRH3KDM4EOPRK1 | |
| SCHEMBL3745442 | 0.69 | RXFP1 (0.36) | HRH3RXFP1MEN1KMT2AMAPT | |
| SCHEMBL4349529 | 0.67 | BACE1 (0.36) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL195410 | 0.66 | ALDH1A1 (0.42) | PDE3BPDE3ARXFP1HTR3AKDM4E | |
| SCHEMBL7094488 | 0.65 | RAB9A (0.38) | PDE3BPDE3ARXFP1KDM4EMEN1 | |
| SCHEMBL11057311 | 0.63 | ATM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474774-A | Acridone substituted phosphorus compounds, compositions containing same and insecticidal method of use | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |