Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13952875 | 0.85 | MAPT (0.66) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL12643745 | 0.84 | MAPT (0.64) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL13159342 | 0.83 | MAPT (0.68) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL26311954 | 0.79 | MAPT (0.83) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL25245380 | 0.78 | MAPT (0.68) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL3752417 | 0.74 | MAOB (0.52) | MAOBMAOA | |
| SCHEMBL3735320 | 0.74 | MAOB (0.53) | MAOBMAOAMOGAT2 | |
| SCHEMBL3747899 | 0.74 | XDH (0.63) | MAOBMAOA | |
| SCHEMBL918880 | 0.73 | MAPT (0.69) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7619627 | 0.73 | MAPT (0.69) | MAPTKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |