Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25524540 | 0.84 | PTPN1 (0.50) | MAOAPDK2BCHEACHE | |
| SCHEMBL23960775 | 0.84 | PTPN1 (0.50) | MAOAPDK2BCHEACHE | |
| SCHEMBL25524541 | 0.84 | PTPN1 (0.50) | MAOAPDK2BCHEACHE | |
| SCHEMBL30426252 | 0.77 | MAPT (0.56) | — | |
| SCHEMBL17796880 | 0.77 | MAPT (0.56) | — | |
| SCHEMBL28585350 | 0.76 | MAOA (0.55) | MAOAPDK2BCHE | |
| SCHEMBL7164713 | 0.75 | MAOA (0.53) | MAOBMAOAPDK2BCHEACHE | |
| SCHEMBL3745581 | 0.74 | MAPT (0.64) | MAOBMAOA | |
| SCHEMBL17899374 | 0.72 | MAPT (0.50) | MAOBMAOA | |
| SCHEMBL10623445 | 0.71 | ALDH1A1 (0.64) | MAOBMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |