Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 5/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748480 | 0.88 | CTSV (0.58) | MAOBMAOACYP2D6CTSVCTSL | |
| SCHEMBL13438381 | 0.85 | MAOB (0.53) | MAOBMAOACYP2D6CTSVCTSL | |
| SCHEMBL3738315 | 0.82 | MAOB (0.47) | MAOBMAOACYP2D6CTSVCTSL | |
| SCHEMBL3747899 | 0.81 | XDH (0.63) | MAOBMAOAXDHALDH2 | |
| SCHEMBL3745105 | 0.77 | MDH2 (0.60) | — | |
| SCHEMBL13438382 | 0.76 | MAOB (0.42) | MAOBMAOACYP2D6CTSVCTSL | |
| SCHEMBL3735330 | 0.76 | MAOB (0.59) | MAOBXDH | |
| SCHEMBL3741475 | 0.75 | MAOB (0.47) | MAOB | |
| SCHEMBL1182220 | 0.74 | MAOA (0.46) | MAOBMAOACTSVCTSLALDH2 | |
| SCHEMBL12758557 | 0.74 | ALDH1A1 (0.52) | MAOACYP2D6XDHALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |