SCHEMBL3745751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3755948	0.82	KCNA5 (0.55)	KCNH2KCNA5SCN9AMAPTPOLB
	SCHEMBL3756742	0.79	KCNA5 (0.68)	KCNH2KCNA5
	SCHEMBL3748973	0.78	KCNA5 (0.57)	KCNH2KCNA5SCN9ATP53SMN1; SMN2
	SCHEMBL3755040	0.76	KCNH2 (0.58)	KCNH2KCNA5SCN9ASCN5A
	SCHEMBL3763242	0.73	KCNA5 (1.00)	KCNH2KCNA5
	SCHEMBL3751859	0.72	KCNA5 (0.67)	KCNH2KCNA5SCN9ASCN5A
	SCHEMBL3762841	0.72	KCNA5 (0.58)	KCNH2KCNA5SCN9ATP53SCN5A
	SCHEMBL3755957	0.71	SCN9A (0.61)	KCNH2KCNA5SCN9ASCN5A
	SCHEMBL3943527	0.71	KCNA5 (0.56)	KCNH2KCNA5SCN9ASCN5AKMT2A
	SCHEMBL3750606	0.69	ALDH1A1 (0.60)	KCNH2SCN9ATP53POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.