SCHEMBL3746342

SCHEMBL3746342

CC(C)(c1cc(Br)c(OCC(O)COc2c(Br)cc(C(C)(C)c3cc(Br)c(OCC4CO4)c(Br)c3)cc2Br)c(Br)c1)c1cc(Br)c(OCC2CO2)c(Br)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
TSHR P16473 5/20 0.46
MAPT P10636 4/20 0.46
HIF1A Q16665 4/20 0.46
HPGD P15428 3/20 0.46
TP53 P04637 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.46
PPARG P37231 1/20 0.46
GLA P06280 2/20 0.35
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085712 0.96 ALDH1A1 (0.47) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL14601522 0.96 ALDH1A1 (0.47) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL677953 0.96 ALDH1A1 (0.47) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL13003246 0.95 ALDH1A1 (0.46) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL15788352 0.95 ALDH1A1 (0.46) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL676687 0.94 ALDH1A1 (0.47) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL14601521 0.93 ALDH1A1 (0.44) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL13238280 0.91 KMT2A (0.52) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL16727407 0.90 ALDH1A1 (0.42) ALDH1A1TSHRMAPTHIF1AHPGD
SCHEMBL16727408 0.90 ALDH1A1 (0.42) ALDH1A1TSHRMAPTHIF1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080275170-A1 METAL OXIDE NANOPARTICLES, METHODS OF MAKING, AND METHODS OF USE CITIBANK, N.A., AS COLLATERAL AGENT 2008-11-06 US claimed
EP-1954732-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS General Electric Company (US) 2008-08-13 EP claimed
WO-2007001811-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS GENERAL ELECTRIC COMPANY (US) 2007-01-04 WO claimed
US-20060293463-A1 Compositions for brightness enhancing films GENERAL ELECTRIC COMPANY 2006-12-28 US claimed
EP-1631603-B1 CURABLE (METH)ACRYLATE COMPOSITIONS GEN ELECTRIC (US) 2006-11-22 EP claimed
US-7087659-B2 Curable (meth)acrylate compositions GENERAL ELECTRICAL (US) 2006-08-08 US claimed
US-6833391-B1 Comprising three monomers having highly brominated phenyl, arylether and bisphenol A or F functionality and initiator; light management films; high refractive index; brightness GENERAL ELECTRIC COMPANY 2004-12-21 US claimed
US-20040249100-A1 CURABLE (METH)ACRYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2004-12-09 US claimed
US-20040242720-A1 Curable (meth)acrylate compositions CITIBANK, N.A., AS COLLATERAL AGENT 2004-12-02 US claimed
US-20230323087-A1 Antimony Trioxide Free Flame Retardant Polymer Composition LANXESS CORPORATION (US) 2023-10-12 US disclosed
US-9631144-B2 Flame retardant composition BROMINE COMPOUNDS LTD. (IL) 2017-04-25 US disclosed
US-9631144-B2 Flame retardant composition BROMINE COMPOUNDS LTD. (IL) 2017-04-25 US disclosed
US-9315731-B2 High impact polystyrene flame retarded compositions BROMINE COMPOUNDS LTD. (IL) 2016-04-19 US disclosed
US-9315731-B2 High impact polystyrene flame retarded compositions BROMINE COMPOUNDS LTD. (IL) 2016-04-19 US disclosed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed
EP-1510557-A2 Metal oxide nanoparticles GENERAL ELECTRIC COMPANY (US) 2005-03-02 EP disclosed
US-6833391-B1 Comprising three monomers having highly brominated phenyl, arylether and bisphenol A or F functionality and initiator; light management films; high refractive index; brightness GENERAL ELECTRIC COMPANY 2004-12-21 US disclosed
WO-2004106396-A1 CURABLE (METH)ACRYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2004-12-09 WO disclosed
US-20040249100-A1 CURABLE (METH)ACRYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2004-12-09 US disclosed
US-20040242720-A1 Curable (meth)acrylate compositions CITIBANK, N.A., AS COLLATERAL AGENT 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom MACF1, WASF2, THEM6 ALDH1A1 1014/4885TSHR 4739/4885MAPT 488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.