Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739621 | 0.90 | AR (0.46) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL3749819 | 0.88 | AR (0.48) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL3743556 | 0.83 | AR (0.47) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL23995539 | 0.78 | AR (0.48) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL4175149 | 0.78 | CHEK1 (0.53) | ARHTR2A | |
| Hydrochloric Acid SCHEMBL4182890 | 0.77 | CHEK1 (0.53) | ARHTR2A | |
| SCHEMBL286396 | 0.75 | KCNJ1 (0.49) | ARALDH1A1KDM4EUSP2PGR | |
| SCHEMBL4734994 | 0.73 | QDPR (0.46) | ARALDH1A1KDM4EUSP2HTR2A | |
| SCHEMBL11157201 | 0.71 | ALDH1A1 (0.50) | ARALDH1A1KDM4EUSP2HTR2A | |
| SCHEMBL7290107 | 0.70 | ALDH1A1 (0.48) | ARALDH1A1KDM4EUSP2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |