Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.57 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697228 | 0.92 | CES1 (0.56) | MAOAMAOBCES1TGM2 | |
| SCHEMBL31016529 | 0.83 | CES1 (0.55) | MAOAMAOBPTPRCTLK2CES1 | |
| SCHEMBL11422252 | 0.78 | ATM (0.53) | MAOAMAOBPTPRCTLK2ATM | |
| SCHEMBL13849150 | 0.75 | TTR (0.63) | PTPRCATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL31016521 | 0.74 | CES1 (0.49) | MAOAMAOBCES1TGM2ALDH1A1 | |
| SCHEMBL30183643 | 0.74 | TGM2 (0.51) | MAOAMAOBPTPRCCES1TDP1 | |
| SCHEMBL20594709 | 0.74 | TGM2 (0.51) | MAOAMAOBPTPRCCES1TDP1 | |
| SCHEMBL27560697 | 0.74 | TTR (0.72) | PTPRCATMTDP1L3MBTL1ALDH1A1 | |
| Isatin SCHEMBL13725994 | 0.73 | MAOA (0.83) | MAOAMAOBTDP1TGM2CASP3 | |
| SCHEMBL5783842 | 0.73 | TGM2 (0.65) | MAOAMAOBTLK2CES1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829567-B2 | Imino-indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-09 | — | — | US | disclosed |
| US-20090111987-A1 | Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-04-30 | — | — | US | disclosed |
| WO-1999065875-A1 | TELOMERASE INHIBITORS | GERON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111987-A1 | Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | IMPA1, IMPDH1, IPO5 | MAOA 2622/4885MAOB 1713/4885PTPRC 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.