Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.56 |
| ▸ | TGM2 | P21980 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 7/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3747686 | 0.92 | MAOA (0.57) | CES1TGM2MAOAMAOB | |
| SCHEMBL31016529 | 0.87 | CES1 (0.55) | CES1TGM2MAOAMAOBSMYD3 | |
| SCHEMBL30183643 | 0.81 | TGM2 (0.51) | CES1TGM2MAOAMAOBCA12 | |
| SCHEMBL20594709 | 0.81 | TGM2 (0.51) | CES1TGM2MAOAMAOBCA12 | |
| SCHEMBL31016521 | 0.81 | CES1 (0.49) | CES1TGM2MAOAMAOBBCHE | |
| SCHEMBL23577870 | 0.77 | CA12 (0.50) | CES1TGM2MAOACA12CA1 | |
| SCHEMBL5783842 | 0.76 | TGM2 (0.65) | CES1TGM2MAOAMAOBSMYD3 | |
| SCHEMBL3748949 | 0.76 | CES1 (0.47) | CES1TGM2MAOAMAOBBCHE | |
| SCHEMBL5323182 | 0.76 | CES1 (0.60) | CES1TGM2MAOAMAOBCA12 | |
| SCHEMBL5893915 | 0.74 | SMYD3 (0.55) | CES1TGM2MAOAMAOBSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362579-B1 | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-05-24 | — | — | EP | claimed |
| EP-1362579-A1 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-11-19 | — | — | EP | claimed |
| EP-1362579-B1 | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-05-24 | — | — | EP | disclosed |
| EP-1362579-A1 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-11-19 | — | — | EP | disclosed |