Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL28871054 | 0.82 | THRB (0.58) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL40718 | 0.80 | THRB (0.67) | THRBHCAR2AKR1B10AKR1B1NPC1 | |
| SCHEMBL149640 | 0.78 | THRB (0.59) | THRBHCAR2AKR1B10AKR1B1NPC1 | |
| SCHEMBL24788139 | 0.76 | THRB (0.46) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Carbon Monoxide SCHEMBL10707595 | 0.76 | THRB (0.61) | THRBHCAR2AKR1B10AKR1B1NPC1 | |
| Ethylene Glycol SCHEMBL6491859 | 0.76 | THRB (0.61) | THRBHCAR2AKR1B10AKR1B1NPC1 | |
| SCHEMBL12648248 | 0.76 | THRB (0.48) | THRBHCAR2AKR1B10AKR1B1NPC1 | |
| SCHEMBL9806249 | 0.76 | TSHR (0.59) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Methacrylic Acid SCHEMBL7262507 | 0.75 | THRB (0.56) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL144847 | 0.75 | THRB (0.59) | THRBHCAR2AKR1B10AKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838188-B2 | Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20070231720-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2007-10-04 | — | — | US | disclosed |