Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 15/20 | 0.54 |
| ▸ | GAA | P10253 | 15/20 | 0.54 |
| ▸ | SI | P14410 | 15/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 15/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CBFB | Q13951 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516716 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL1170892 | 0.80 | MGAM (0.71) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL8601516 | 0.80 | TDP1 (0.50) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL3967441 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL353891 | 0.76 | PARP1 (0.56) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL3968918 | 0.76 | MEN1 (0.42) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL3968187 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL7969798 | 0.75 | DHODH (0.58) | ALDH1A1TDP1 | |
| SCHEMBL21212784 | 0.75 | PDK2 (0.40) | ALDH1A1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL12195163 | 0.75 | ALDH1A1 (0.71) | ALDH1A1TDP1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2410010-B1 | Improved lead-free insulation compositions containing metallocene polymers | GEN CABLE TECHNOLOGIES CORP (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-1948728-B1 | IMPROVED LEAD-FREE INSULATION COMPOSITIONS CONTAINING METALLOCENE POLYMERS | GEN CABLE TECHNOLOGIES CORP (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2311049-B1 | IMPROVED HARD GRADE EPR INSULATION COMPOSITIONS | GEN CABLE TECHNOLOGIES CORP (US) | 2014-08-27 | — | — | EP | disclosed |
| EP-2410010-A1 | Improved lead-free insulation compositions containing metallocene polymers | General Cable Technologies Corporation (US) | 2012-01-25 | — | — | EP | disclosed |
| US-7989126-B2 | Metal mercaptoimidazoles containing photoconductors | XEROX CORPORATION (US) | 2011-08-02 | — | — | US | disclosed |
| EP-2311049-A2 | IMPROVED HARD GRADE EPR INSULATION COMPOSITIONS | General Cable Technologies Corporation (US) | 2011-04-20 | — | — | EP | disclosed |
| US-7858711-B2 | Lead-free insulation compositions containing metallocene polymers | General CableTechnologies Corporation (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100022683-A1 | HARD GRADE EPR INSULATION COMPOSITIONS | GENERAL CABLE TECHNOLOGIES CORPORATION (US) | 2010-01-28 | — | — | US | disclosed |
| WO-2010011418-A2 | IMPROVED HARD GRADE EPR INSULATION COMPOSITIONS | GENERAL CABLE TECHNOLOGIES CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |
| US-20090274965-A1 | METAL MERCAPTOIMIDAZOLES CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-11-05 | — | — | US | disclosed |
| US-7473742-B2 | Lead-free insulation compositions containing metallocene polymers | GENERAL CABLE TECHNOLOGIES CORP. (US) | 2009-01-06 | — | — | US | disclosed |
| EP-1948728-A2 | IMPROVED LEAD-FREE INSULATION COMPOSITIONS CONTAINING METALLOCENE POLYMERS | General Cable Technologies Corporation (US) | 2008-07-30 | — | — | EP | disclosed |
| US-20070213433-A1 | Polymer may be metallocene based, non metallocene based, hindered amine light stabilizers, mercapto compounds, and optionally, amine antioxidants, improved electrical and mechanical properties; without use of custom polymers such as elastomer terpolymer containing 5-vinyl-2-norbornene as base resin | GENERAL CABLE TECHNOLOGIES CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070100032-A1 | Lead-free insulation compositions containing metallocene polymers | GENERAL CABLE TECHNOLOGIES CORPORATION | 2007-05-03 | — | — | US | disclosed |
| WO-2007050688-A2 | IMPROVED LEAD-FREE INSULATION COMPOSITIONS CONTAINING METALLOCENE POLYMERS | GENERAL CABLE TECHNOLOGIES CORPORATION (US) | 2007-05-03 | — | — | WO | disclosed |