Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374823 | 0.80 | ALDH1A1 (0.59) | TDP1GAAALDH1A1ADORA3ADORA2A | |
| SCHEMBL3967441 | 0.79 | ALDH1A1 (0.40) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL6842031 | 0.76 | PARP1 (0.66) | PARP1 | |
| SCHEMBL1013125 | 0.76 | PARP1 (0.59) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL30291834 | 0.75 | MEN1 (0.58) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3287778 | 0.75 | MEN1 (0.58) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3968187 | 0.75 | ALDH1A1 (0.43) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3968918 | 0.75 | MEN1 (0.42) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6120896 | 0.74 | PARP1 (0.57) | TDP1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL21212784 | 0.73 | PDK2 (0.40) | TDP1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |