SCHEMBL374825

SCHEMBL374825

Cc1nc2ccccc2n1S

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.55
MAPK1 P28482 1/20 0.55
TSHR P16473 2/20 0.52
LMNA P02545 4/20 0.50
TP53 P04637 2/20 0.50
TNF P01375 1/20 0.50
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
HSD17B10 Q99714 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.47
GALR3 O60755 3/20 0.47
NR2F2 P24468 3/20 0.47
RAB9A P51151 2/20 0.47
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
ALDH3A1 P30838 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL353890 0.76 SMN1; SMN2 (0.63) HTTMAPK1TSHRLMNATP53
SCHEMBL23731899 0.76 SMN1; SMN2 (0.42) HTTMAPK1TSHRLMNATP53
SCHEMBL20019195 0.75 KDM4E (0.54) TSHRLMNATP53KDM4EPOLB
SCHEMBL4597356 0.75 NLRP3 (0.42) LMNAKDM4EMAPTHSD17B10RAB9A
SCHEMBL18347137 0.74 HTT (0.55) HTTMAPK1TSHRLMNATP53
SCHEMBL8956416 0.74 SMN1; SMN2 (0.61) HTTMAPK1LMNATNFKDM4E
SCHEMBL8422526 0.74 HTT (0.55) HTTMAPK1TSHRLMNATP53
SCHEMBL5144258 0.74 NOS2 (0.61) HTTMAPK1TSHRLMNATP53
Bromide SCHEMBL5318089 0.74 SMN1; SMN2 (0.61) HTTMAPK1TSHRLMNATP53
Iodide SCHEMBL336205 0.74 SMN1; SMN2 (0.61) HTTMAPK1TSHRLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113463074-B Copper deposition composition and copper deposition method 广东硕成科技股份有限公司 2022-06-14 CN claimed
CN-113801259-A Preparation method and application of benzimidazole macroporous adsorption resin 安徽皖东树脂科技有限公司 2021-12-17 CN claimed
CN-110184631-B Cyanide-free gold plating electroplating solution and preparation method and electroplating process thereof 广州达志新材料科技有限公司 2021-05-04 CN claimed
CN-110029374-B Cyanide-free alkaline copper plating electroplating solution and electroplating process 广州达志新材料科技有限公司 2021-05-04 CN claimed
CN-108358953-A The complex and its application of copper and Imidazopyridine compound 沈阳药科大学 2018-08-03 CN claimed
CN-108299473-A Complex and its application of the copper with the benzimidazoles compound containing pyridine 沈阳药科大学 2018-07-20 CN claimed
CN-107235961-A A kind of preparation method of esomeprazole 武汉励合生物医药科技有限公司 2017-10-10 CN claimed
CN-106543146-A A kind of preparation method of R-lansoprazole 石家庄市度智医药科技有限公司 2017-03-29 CN claimed
CN-103698430-B Esomeprazole sodium and method for detecting impurity content in esomeprazole sodium for injection JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO LTD 2015-01-21 CN claimed
CN-103698430-A Esomeprazole sodium and method for detecting impurity content in esomeprazole sodium for injection JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO LTD 2014-04-02 CN claimed
US-6359230-B1 Automotive-wire insulation CHAMPLAIN CABLE CORPORATION 2002-03-19 US claimed
JP-58120653-A None JP disclosed
US-20260015469-A1 HEAT-RESISTANT SILANE CROSSLINKED RESIN FORMED BODY, SILANE CROSSLINKABLE RESIN COMPOSITION, METHOD OF PRODUCING SAME, AND WIRING MATERIAL FURUKAWA ELECTRIC CO., LTD. (JP) 2026-01-15 US disclosed
WO-2024195048-A1 HEAT-RESISTANT SILANE-CROSSLINKED RESIN MOLDED ARTICLE, SILANE-CROSSLINKABLE RESIN COMPOSITION, METHODS FOR PRODUCING SAME, AND WIRING MATERIAL 古河電気工業株式会社 2024-09-26 WO disclosed
CN-113801259-A Preparation method and application of benzimidazole macroporous adsorption resin 安徽皖东树脂科技有限公司 2021-12-17 CN disclosed
JP-S58120653-A RUBBER ANTIOXIDANT SUMITOMO CHEM CO LTD 1983-07-18 JP disclosed
US-4245033-A AN ORGANIC SILVER SALT, A HALIDE AND A SULFUR COMPOUND EXPOSED TO FORM A SILVER IMAGE OF HIGH CONTRAST AND STABILITY CANON KABUSHIKI KAISHA (JP) 1981-01-13 US disclosed
US-4209418-A CLEANING SOLUTIONS FOR METAL INDUSTRIAL EQUIPMENT UNION CARBIDE CORPORATION (US) 1980-06-24 US disclosed
US-4000275-A BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES ELI LILLY AND COMPANY (US) 1976-12-28 US disclosed
US-4000275-A BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES ELI LILLY AND COMPANY (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015469-A1 HEAT-RESISTANT SILANE CROSSLINKED RESIN FORMED BODY, SILANE CROSSLINKABLE RESIN COMPOSITION, METHOD OF PRODUCING SAME, AND WIRING MATERIAL SEM1, PCNA, RPL34 HTT 2743/4885MAPK1 3303/4885TSHR 4625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.