SCHEMBL3749145

SCHEMBL3749145

CC(C)COc1c(F)c(F)c(S(=O)(=O)O)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
KAT6A Q92794 1/20 0.32
FABP3 P05413 1/20 0.31
FABP4 P15090 1/20 0.31
FABP5 Q01469 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17399697 0.91 KAT6A (0.33) LMNACA12CA1CA2CA9
SCHEMBL14491287 0.79 CA1 (0.32) CA12CA1CA2CA9ALDH1A1
SCHEMBL13676826 0.78 ALDH1A1 (0.32) LMNAKDM4EALDH1A1MAPTHTT
SCHEMBL13713623 0.77 TP53 (0.36) MAPT
SCHEMBL13713630 0.76 TP53 (0.36)
SCHEMBL13048595 0.76 FABP3 (0.33) CA1CA2CA9FABP3FABP4
SCHEMBL13713624 0.75 TP53 (0.35)
SCHEMBL13713629 0.75 RECQL (0.32)
SCHEMBL14278399 0.74 CA1 (0.38) LMNACA12CA1CA2CA9
SCHEMBL15497022 0.74 TSHR (0.34) LMNAKAT6AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833690-B2 Photoacid generators and lithographic resists comprising the same THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) 2010-11-16 US disclosed
US-20070117043-A1 Photoacid generators and lithographic resists comprising the same NATIONAL SCIENCE FOUNDATION 2007-05-24 US disclosed