Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810778 | 0.86 | TAAR1 (0.53) | TAAR1RIPK1CTSBCTSSCTSK | |
| SCHEMBL3012881 | 0.85 | TAAR1 (0.55) | TAAR1RIPK1CTSBCTSSCTSK | |
| SCHEMBL1704199 | 0.83 | TAAR1 (0.55) | TAAR1RIPK1SIGMAR1FFAR1FFAR4 | |
| SCHEMBL4398498 | 0.78 | RIPK1 (0.53) | TAAR1RIPK1CTSBCTSSCTSK | |
| SCHEMBL3241377 | 0.77 | HDAC1 (0.43) | TAAR1RIPK1CTSBCTSSCTSK | |
| SCHEMBL20718841 | 0.77 | AAK1 (0.35) | ACHEAAK1 | |
| SCHEMBL2176070 | 0.77 | RIPK1 (0.63) | TAAR1RIPK1CTSBCTSSCTSK | |
| SCHEMBL902744 | 0.76 | L3MBTL1 (0.47) | TAAR1RIPK1CTSBCTSSCTSK | |
| SCHEMBL4711023 | 0.76 | TAAR1 (0.41) | TAAR1RIPK1CTSBCTSSCTSK | |
| SCHEMBL4819083 | 0.76 | TAAR1 (0.41) | TAAR1RIPK1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | KCNH1, KCNH2, KCNQ2 | TAAR1 848/4885RIPK1 3747/4885CTSB 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.