Water

Water

SCHEMBL3751250

C=CC(c1ccccc1)[N+](C)(C)C.[OH-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
LMNA P02545 2/20 0.34
KDM4E B2RXH2 4/20 0.33
MAPT P10636 4/20 0.33
CYP3A4 P08684 3/20 0.33
ALOX15 P16050 3/20 0.33
ALDH1A1 P00352 3/20 0.33
SCN1A P35498 2/20 0.33
SCN2A Q99250 2/20 0.33
SCN3A Q9NY46 2/20 0.33
CYP2C19 P33261 1/20 0.33
HPGD P15428 3/20 0.33
USP2 O75604 2/20 0.33
TP53 P04637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALOX12 P18054 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL210755 0.98 CYP1A2 (0.37) CYP1A2LMNAKDM4EMAPTCYP3A4
Hydrochloric Acid SCHEMBL22686139 0.96 CYP1A2 (0.36) CYP1A2LMNAKDM4EMAPTCYP3A4
Iodide SCHEMBL31397630 0.96 SCN1A (0.36) CYP1A2LMNAKDM4EMAPTCYP3A4
Bromide SCHEMBL3466725 0.96 CYP1A2 (0.36) CYP1A2LMNAKDM4EMAPTCYP3A4
Hydrochloric Acid SCHEMBL58307 0.96 CYP1A2 (0.36) CYP1A2LMNAKDM4EMAPTCYP3A4
Fluoride Ion SCHEMBL6316234 0.96 CYP1A2 (0.36) CYP1A2LMNAKDM4EMAPTCYP3A4
Hydrochloric Acid SCHEMBL9501111 0.94 CYP1A2 (0.35) CYP1A2LMNAKDM4EMAPTCYP3A4
SCHEMBL25207681 0.90 CYP1A2 (0.33) CYP1A2LMNAKDM4EMAPTCYP3A4
SCHEMBL9615835 0.90 CYP1A2 (0.33) CYP1A2LMNAKDM4EMAPTCYP3A4
Sulfuric Acid SCHEMBL10945799 0.87 CYP1A2 (0.35) CYP1A2LMNAKDM4EMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200030752-A1 MEMBRANES FOR GAS SEPARATION OHIO STATE INNOVATION FOUNDATION 2020-01-30 US claimed
EP-3344372-A1 MEMBRANES FOR GAS SEPARATION Ohio State Innovation Foundation (US) 2018-07-11 EP claimed
US-20170056839-A1 MEMBRANES FOR GAS SEPARATION OHIO STATE INNOVATION FOUNDATION 2017-03-02 US claimed
EP-3054034-A1 AMINE-CONTAINING ELECTROLYTE FOR ELECTROCHEMICAL DEVICES Ginkgo Investments Limited (GB) 2016-08-10 EP claimed
EP-1535362-B1 ALKALINE CELL WITH POLYMER ELECTROLYTE GILLETTE CO (US) 2007-05-16 EP claimed
WO-2006109311-A2 ENZYME-CHANNELING BASED ELECTROCHEMICAL BIOSENSORS RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-10-19 WO claimed
CN-1672285-A Alkaline cell with polymer electrolyte GILLETTE CO (US) 2005-09-21 CN claimed
US-6916577-B2 Zinc anode, manganese dioxide cathode. and an electrolyte comprising polyvinylbenzyltrimethylammonium hydroxide. THE GILLETTE COMPANY (US) 2005-07-12 US claimed
EP-1535362-A2 ALKALINE CELL WITH POLYMER ELECTROLYTE THE GILLETTE COMPANY (US) 2005-06-01 EP claimed
US-20040023110-A1 Zinc anode, manganese dioxide cathode. and an electrolyte comprising polyvinylbenzyltrimethylammonium hydroxide. DURACELL U.S. OPERATIONS, INC. 2004-02-05 US claimed
WO-2004012281-A2 ALKALINE CELL WITH POLYMER ELECTROLYTE THE GILLETTE COMPANY (US) 2004-02-05 WO claimed
US-6638480-B2 Determination of total dissolved solids in sample; obtain sample, incubate with color indicator, monitor for color adjustment, determination of dissolved solid ENVIRONMENTAL TEST SYSTEMS, INC. 2003-10-28 US claimed
US-20020102740-A1 High sensitivity test system for the colorimetric determination of specific gravity or total dissolved solids in aqueous samples HACH COMPANY 2002-08-01 US claimed
US-4140659-A ION EXCHANGE RESINS ROHM AND HAAS COMPANY (US) 1979-02-20 US claimed
EP-4717716-A1 POLYMERIZABLE COMPOSITION, ION EXCHANGE RESIN, ION EXCHANGE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, AND HYDROGEN PRODUCTION DEVICE TOKUYAMA CORPORATION (JP) 2026-04-01 EP disclosed
WO-2024241769-A1 POLYMERIZABLE COMPOSITION, ION EXCHANGE RESIN, ION EXCHANGE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, AND HYDROGEN PRODUCTION DEVICE 株式会社トクヤマ 2024-11-28 WO disclosed
WO-2024162071-A1 COMPOSITION, POLYMERIZABLE COMPOSITION, ION-EXCHANGE RESIN, ION-EXCHANGE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, HYDROGEN PRODUCTION DEVICE, AND MANUFACTURING METHOD OF ION EXCHANGE MEMBRANE 株式会社トクヤマ 2024-08-08 WO disclosed
EP-0013113-A1 A process and apparatus for the production of electrical energy from the neutralization of acid and base in a bipolar membrane cell ALLIED CORPORATION (US) 1980-07-09 EP disclosed
US-4140659-A ION EXCHANGE RESINS ROHM AND HAAS COMPANY (US) 1979-02-20 US disclosed
US-4137264-A CROSSLINKING, CATIONIC EXCHANGE RESINS ROHM AND HAAS COMPANY (US) 1979-01-30 US disclosed