Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324864 | 0.95 | — | — | |
| Methyl Alcohol SCHEMBL28086992 | 0.92 | LMNA (0.46) | LMNACA5ACA5BALDH1A1L3MBTL1 | |
| SCHEMBL28138742 | 0.83 | LMNA (0.39) | LMNAALDH1A1L3MBTL1TDP1TSHR | |
| Nitric Acid SCHEMBL10950363 | 0.79 | LMNA (0.44) | LMNACA5ACA5BALDH1A1TDP1 | |
| Nitric Acid SCHEMBL10936105 | 0.79 | LMNA (0.44) | LMNACA5ACA5BALDH1A1TDP1 | |
| Nitric Acid SCHEMBL28389404 | 0.78 | CA5A (0.47) | LMNACA5ACA5BALDH1A1TDP1 | |
| Nitric Acid SCHEMBL5538160 | 0.78 | CA5A (0.47) | LMNACA5ACA5BALDH1A1TDP1 | |
| Nitric Acid SCHEMBL11117097 | 0.78 | CA5A (0.47) | LMNACA5ACA5BALDH1A1TDP1 | |
| Nitric Acid SCHEMBL442180 | 0.78 | CA5A (0.47) | LMNACA5ACA5BALDH1A1TDP1 | |
| Deanol SCHEMBL11140865 | 0.76 | CA5A (0.44) | LMNACA5ACA5BALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100293841-A1 | Nitrated non-cyclic N-Alkane scaffolds with differentiated-mean combustive equivalencies as high energy density fuel improvers | FUELTEK, INC. | 2010-11-25 | — | — | US | claimed |
| EP-0101093-A2 | Diesel fuel composition | ETHYL CORPORATION (US) | 1984-02-22 | — | — | EP | claimed |
| US-4417903-A | NITRO-ALKYLNITRATE ESTER ANTIKNOCK ADDITIVES | ETHYL CORPORATION (US) | 1983-11-29 | — | — | US | claimed |
| US-20100293841-A1 | Nitrated non-cyclic N-Alkane scaffolds with differentiated-mean combustive equivalencies as high energy density fuel improvers | FUELTEK, INC. | 2010-11-25 | — | — | US | disclosed |
| US-5258049-A | Nitric acid esters of phenylethanol | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0195462-A2 | Diesel fuel composition | ETHYL CORPORATION (US) | 1986-09-24 | — | — | EP | disclosed |
| EP-0101093-A2 | Diesel fuel composition | ETHYL CORPORATION (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4417903-A | NITRO-ALKYLNITRATE ESTER ANTIKNOCK ADDITIVES | ETHYL CORPORATION (US) | 1983-11-29 | — | — | US | disclosed |
| US-4417903-A | NITRO-ALKYLNITRATE ESTER ANTIKNOCK ADDITIVES | ETHYL CORPORATION (US) | 1983-11-29 | — | — | US | disclosed |