Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338812 | 0.83 | ADRB2 (0.45) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL17102803 | 0.78 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL3260445 | 0.75 | DNM1 (0.52) | DNM1TSHRALDH1A1CA1CA2 | |
| SCHEMBL3752173 | 0.74 | ADRB2 (0.38) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL11101061 | 0.72 | DNM1 (0.56) | DNM1TSHRCA1CA2THRB | |
| SCHEMBL6180238 | 0.72 | DNM1 (0.56) | DNM1TSHRCA1CA2THRB | |
| SCHEMBL18240005 | 0.72 | DNM1 (0.56) | DNM1TSHRCA1CA2THRB | |
| SCHEMBL187631 | 0.72 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DNM1TSHR | |
| SCHEMBL7778179 | 0.72 | DNM1 (0.56) | DNM1TSHRCA1CA2THRB | |
| SCHEMBL4594523 | 0.72 | DNM1 (0.56) | DNM1TSHRCA1CA2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297049-A1 | LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND AND COMPOSITION AND DEVICE | L'OREAL S.A. (FR) | 2010-11-25 | — | — | US | disclosed |