SCHEMBL3752543

SCHEMBL3752543

CC1(C)c2ccc3ccccc3c2-c2ccc3ccccc3c21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
MAPT P10636 4/20 0.42
KDM4E B2RXH2 4/20 0.42
LMNA P02545 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
HTT P42858 2/20 0.42
THRB P10828 1/20 0.42
APEX1 P27695 1/20 0.42
RECQL P46063 1/20 0.42
DNMT1 P26358 1/20 0.41
ALDH1A1 P00352 7/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
RAB9A P51151 1/20 0.40
CYP2A6 P11509 3/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPK1 P28482 3/20 0.38
CYP1A2 P05177 4/20 0.36
HPGD P15428 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13055915 0.84 MEN1 (0.33) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL17852130 0.83 DNMT1 (0.37) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL20581764 0.83 ALDH1A1 (0.44) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL23743376 0.83 CYP2A6 (0.44) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL19196987 0.83 MEN1 (0.33) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL1012419 0.81 TRPM4 (0.40) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL19197895 0.81 SOS1 (0.33) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL3748294 0.81 MEN1 (0.52) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL2539931 0.81 CYP2A6 (0.48) MEN1KMT2AMAPTKDM4ELMNA
SCHEMBL21130128 0.80 MAPT (0.40) MEN1KMT2AMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9461260-B2 Organic light emitting device CANON KABUSHIKI KAISHA (JP) 2016-10-04 US disclosed
US-9331296-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-05-03 US disclosed
US-20130264550-A1 ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-10-10 US disclosed
US-20130001542-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-01-03 US disclosed
US-7838130-B2 Aminodibenzofluorene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-11-23 US disclosed
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-10-29 US disclosed
EP-1872173-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME TRANSITIONS OPTICAL, INC. (US) 2008-01-02 EP disclosed
EP-1869140-A1 OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS Johnson and Johnson Vision Care, Inc. (US) 2007-12-26 EP disclosed
WO-2006110513-A1 OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-10-19 WO disclosed
WO-2006110221-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME TRANSITIONS OPTICAL, INC. (US) 2006-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090267491-A1 AMINODIBENZOFLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME L1CAM, DDC, LEF1 MEN1 3340/4885KMT2A 529/4885MAPT 2095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.