Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445790 | 0.78 | MIF (0.56) | CHRNA7NPC1DPP4CASP3SENP8 | |
| SCHEMBL3826204 | 0.75 | ABL1 (0.44) | PDGFRBPDGFRA | |
| SCHEMBL1998033 | 0.74 | HRH4 (0.51) | CHRNA7NPC1DPP4CASP3SENP8 | |
| SCHEMBL21821109 | 0.74 | MEN1 (0.42) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL11157639 | 0.73 | CYP2A6 (0.39) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL632053 | 0.72 | ASIC3 (0.59) | NPC1HRH4 | |
| SCHEMBL21010861 | 0.72 | PDGFRB (0.42) | PDGFRBPDGFRACYP2A6CYP2E1CYP2B6 | |
| SCHEMBL29392239 | 0.72 | ASIC3 (0.59) | NPC1HRH4 | |
| SCHEMBL1257940 | 0.72 | KMO (0.58) | NPC1DPP4 | |
| Hydrochloric Acid SCHEMBL5351409 | 0.72 | CYP2A6 (0.38) | NPC1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919854-B1 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBVIE INC (US) | 2013-09-18 | — | — | EP | disclosed |
| US-7834012-B2 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-01 | — | — | US | disclosed |
| CN-101263107-A | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBOTT LAB (US) | 2008-09-10 | — | — | CN | disclosed |
| EP-1919854-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2008-05-14 | — | — | EP | disclosed |
| CN-101137649-A | Alkinyl-oxypyrimidine used in the form of pesticides | BAYER CROPSCIENCE AG (DE) | 2008-03-05 | — | — | CN | disclosed |
| EP-1846398-A1 | ALKINYL-OXYPYRIMIDINE USED IN THE FORM OF PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
| WO-2007027651-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070049596-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBVIE INC. | 2007-03-01 | — | — | US | disclosed |
| WO-2006072426-A1 | ALKINYL-OXYPYRIMIDINE USED IN THE FORM OF PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049596-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | DPP4, DPP3, DPP7 | CHRNA7 4591/4885NPC1 601/4885DPP4 1/4885 |
| US-20090005403-A1 | Alkinyl-Oxypyrimidines Used in the Form of Pesticides | ALK, DPYD, DDT | CHRNA7 2645/4885NPC1 4696/4885DPP4 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.