Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 10/20 | 0.38 |
| ▸ | TUBB | P07437 | 10/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748378 | 0.90 | PRKAB2 (0.37) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12854876 | 0.88 | HSP90AB1 (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12854869 | 0.86 | KLKB1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14227782 | 0.85 | PRKAB2 (0.38) | PRKAB2ABL1CSF1RLYNPRKAG1 | |
| SCHEMBL12854863 | 0.85 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3757755 | 0.84 | TUBB1 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14227784 | 0.80 | PRKAB2 (0.38) | PRKAB2ABL1CSF1RLYNPRKAG1 | |
| SCHEMBL12854874 | 0.80 | ERN1 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3749411 | 0.78 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3749400 | 0.78 | TUBB1 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557982-B2 | Tubulin polymerisation inhibitors | BIONOMICS LIMITED (AU) | 2013-10-15 | — | — | US | claimed |
| US-20120309768-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2012-12-06 | — | — | US | claimed |
| US-8278290-B2 | Tubulin polymerisation inhibitors | Biononics Limited (AU) | 2012-10-02 | — | — | US | claimed |
| US-20100292190-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2010-11-18 | — | — | US | claimed |
| US-8557982-B2 | Tubulin polymerisation inhibitors | BIONOMICS LIMITED (AU) | 2013-10-15 | — | — | US | disclosed |
| US-8557982-B2 | Tubulin polymerisation inhibitors | BIONOMICS LIMITED (AU) | 2013-10-15 | — | — | US | disclosed |
| US-20120309768-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2012-12-06 | — | — | US | disclosed |
| US-20120309768-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2012-12-06 | — | — | US | disclosed |
| US-8278290-B2 | Tubulin polymerisation inhibitors | Biononics Limited (AU) | 2012-10-02 | — | — | US | disclosed |
| US-8278290-B2 | Tubulin polymerisation inhibitors | Biononics Limited (AU) | 2012-10-02 | — | — | US | disclosed |
| US-8278290-B2 | Tubulin polymerisation inhibitors | Biononics Limited (AU) | 2012-10-02 | — | — | US | disclosed |
| US-20100292190-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2010-11-18 | — | — | US | disclosed |
| US-20100292190-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2010-11-18 | — | — | US | disclosed |
| US-20100292190-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2010-11-18 | — | — | US | disclosed |
| EP-1848704-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | Bionomics Limited (AU) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084338-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | BIONOMICS LIMITED (AU) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292190-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | TUBB1, TUBA1C, TUBB | TUBB4A 14/4885TUBB 3/4885TUBA3C 11/4885 |
| US-20120309768-A1 | NOVEL TUBULIN POLYMERISATION INHIBITORS | TUBB1, TUBA1C, TUBB | TUBB4A 14/4885TUBB 3/4885TUBA3C 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.